HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: RAB6B (Q9NRW1)
Ras-related protein Rab-6B (EC 3.6.5.2)
Gene: RAB6B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 217 Hs			1 208
+	Hs
		924750 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		RAB8B_HUMAN (10-207): 6.35e-89: 261: 38.31
+	Hs
		913994 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		RB11A_HUMAN (7-206): 6.52e-84: 249: 28.71
+	Hs
		924749 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		RAB1C_HUMAN (7-206): 2.98e-84: 249: 35.00
+	Hs
		924599 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		RB11B_HUMAN (7-208): 5.29e-82: 244: 28.91
+	Hs
		557649 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		RB11A_HUMAN (7-206): 6.52e-84: 249: 28.71
+	Hs
		433251 YES_HUMAN (59-215): 4.17e-13: 69.2: 14.91		RAB5A_HUMAN (3-207): 4.67e-89: 262: 40.78
+	Hs
		433295 YES_HUMAN (59-215): 4.17e-13: 69.2: 14.91		RAB5C_HUMAN (3-207): 3.56e-89: 262: 40.98
+	Hs
		592275 ITSN1_HUMAN (137-216): 1.36e-12: 68.1: 25.00		RAB5A_HUMAN (3-207): 4.67e-89: 262: 40.78
+	Hs
		433652 LYN_HUMAN (129-215): 1.44e-11: 65: 22.47		RAB5C_HUMAN (3-207): 3.56e-89: 262: 40.98
+	Hs
		433312 YES_HUMAN (59-215): 4.17e-13: 69.2: 14.91		RB11A_HUMAN (7-206): 6.52e-84: 249: 28.71
+	Hs
		914091 ITSN1_HUMAN (137-216): 1.36e-12: 68.1: 25.00		RB11A_HUMAN (7-206): 6.52e-84: 249: 28.71
+	Hs
		522882 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		RB11A_HUMAN (7-206): 6.52e-84: 249: 28.71
+	Hs
		523004 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		RB11B_HUMAN (7-208): 5.29e-82: 244: 28.91
+	Hs
		433306 YES_HUMAN (59-215): 4.17e-13: 69.2: 14.91		RAB2A_HUMAN (14-191): 5.16e-45: 150: 39.89
+	Hs
		433674 LYN_HUMAN (129-215): 1.44e-11: 65: 22.47		RAB2A_HUMAN (14-191): 5.16e-45: 150: 39.89
+	Hs
		522878 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		RAB2A_HUMAN (14-191): 5.16e-45: 150: 39.89