Protein: YETS4
YEATS domain-containing protein 4 (Glioma-amplified sequence 41) (Gas41) (NuMA-binding protein 1) (NuBI-1) (NuBI1)

Gene: YETS4, YEATS4
Organism: Homo sapiens
Interactions: 183
UniProt ID: O95619

Gene Ontology (top 5):
GO:0000278 - mitotic cell cycle
GO:0000786 - nucleosome
GO:0005200 - structural constituent of cytoskeleton
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

340378

KAT5
Histone acetyltransferase KAT5

7

8

Small-scale

0.749

High

340429

RUVB2
RuvB-like 2

7

8

High-throughput

0.746

High

340430

RUVB1
RuvB-like 1

7

8

High-throughput

0.746

High

340278

MYC
Myc proto-oncogene protein

7

4

Small-scale

0.744

High

340413

DMAP1
DNA methyltransferase 1-associated protein 1

6

8

Small-scale

0.735

High

340388

EP400
E1A-binding protein p400

6

10

Small-scale

0.733

High

340421

MO4L1
Mortality factor 4-like protein 1

6

2

Small-scale

0.732

High

340404

EPC1
Enhancer of polycomb homolog 1

5

3

Small-scale

0.722

High

340403

BRD8
Bromodomain-containing protein 8

5

10

High-throughput

0.718

High

340418

ING3
Inhibitor of growth protein 3

5

5

Small-scale

0.718

High

340431

TRRAP
Transformation/transcription domain-associated protein

5

6

High-throughput

0.718

High

340332

VPS72
Vacuolar protein sorting-associated protein 72 homolog

5

1

Small-scale

0.716

High

340415

MRGBP
MRG/MORF4L-binding protein

7

0

Small-scale

0.714

High

211616

ZNHI1
Zinc finger HIT domain-containing protein 1

7

0

Small-scale

0.712

High

340327

MO4L2
Mortality factor 4-like protein 2

5

2

Small-scale

0.712

High

340320

MBTD1
MBT domain-containing protein 1

6

0

Small-scale

0.705

High

340336

EPC2
Enhancer of polycomb homolog 2

4

3

High-throughput

0.699

High

340350

FOXR1
Forkhead box protein R1

4

1

High-throughput

0.699

High

340352

SRCAP
Helicase SRCAP

4

11

High-throughput

0.699

High

340401

ARP6
Actin-related protein 6

4

8

High-throughput

0.694

High

340379

H2B1A
Histone H2B type 1-A

4

8

High-throughput

0.691

High

340357

JAZF1
Juxtaposed with another zinc finger protein 1

5

0

Small-scale

0.688

High

340284

H2AZ
Histone H2A.Z

4

6

Small-scale

0.683

High

340345

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

4

0

High-throughput

0.667

High

317305

ACL6B
Actin-like protein 6B

3

8

High-throughput

0.667

High

340277

FOS
Protein c-Fos

3

4

High-throughput

0.667

High

340292

FOSL2
Fos-related antigen 2

3

4

High-throughput

0.667

High

340321

GABPA
GA-binding protein alpha chain

3

1

High-throughput

0.667

High

340351

FOXR2
Forkhead box protein R2

3

1

High-throughput

0.667

High

340298

WEE1
Wee1-like protein kinase

4

0

High-throughput

0.664

High

340407

EAF6
Chromatin modification-related protein MEAF6

4

0

High-throughput

0.661

High

340312

MAX
Protein max

3

5

Small-scale

0.656

High

340315

H2B1C
Histone H2B type 1-C/E/F/G/I

3

10

High-throughput

0.640

High

340383

LENG1
Leukocyte receptor cluster member 1

3

0

High-throughput

0.638

High

340326

NUMA1
Nuclear mitotic apparatus protein 1

3

0

Small-scale

0.638

High

340368

ANKK1
Ankyrin repeat and protein kinase domain-containing protein 1

3

0

High-throughput

0.636

High

340286

MYCL
Protein L-Myc

2

5

High-throughput

0.628

High

340310

SNX16
Sorting nexin-16

3

1

High-throughput

0.609

High

246367

KDM1A
Lysine-specific histone demethylase 1A

2

1

Small-scale

0.586

High

340302

FUS
RNA-binding protein FUS

2

0

High-throughput

0.585

High

340359

SUGP1
SURP and G-patch domain-containing protein 1

2

0

High-throughput

0.585

High

340283

TPM1
Tropomyosin alpha-1 chain

2

0

High-throughput

0.580

High

280979

TACC1
Transforming acidic coiled-coil-containing protein 1

1

1

Small-scale

0.573

High

334270

TACC2
Transforming acidic coiled-coil-containing protein 2

1

1

Small-scale

0.561

High

340288

T2FB
General transcription factor IIF subunit 2

1

2

Small-scale

0.561

High

340301

T2FA
General transcription factor IIF subunit 1

1

1

Small-scale

0.561

High

340308

AF10
Protein AF-10

1

7

Small-scale

0.561

High

340322

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

1

Small-scale

0.561

High

340363

AGGF1
Angiogenic factor with G patch and FHA domains 1

2

1

High-throughput

0.558

High

340279

MYCN
N-myc proto-oncogene protein

1

4

Small-scale

0.552

High

340374

AP2B
Transcription factor AP-2-beta

1

0

Small-scale

0.549

High

127748

IKBE
NF-kappa-B inhibitor epsilon

1

1

High-throughput

0.536

High

280445

PR40A
Pre-mRNA-processing factor 40 homolog A

1

1

High-throughput

0.536

High

340276

ACL6A
Actin-like protein 6A

1

6

High-throughput

0.536

High

340281

S10A6
Protein S100-A6

1

1

High-throughput

0.536

High

340287

K2C5
Keratin, type II cytoskeletal 5

1

1

High-throughput

0.536

High

340291

FOSL1
Fos-related antigen 1

1

4

High-throughput

0.536

High

340303

K22E
Keratin, type II cytoskeletal 2 epidermal

1

1

High-throughput

0.536

High

340305

MTOR
Serine/threonine-protein kinase mTOR

1

6

High-throughput

0.536

High

340309

AF17
Protein AF-17

1

7

High-throughput

0.536

High

340311

ACTB
Actin, cytoplasmic 1

1

6

High-throughput

0.536

High

340317

CSK21
Casein kinase II subunit alpha

1

2

High-throughput

0.536

High

340339

ACTBL
Beta-actin-like protein 2

1

6

High-throughput

0.536

High

340362

H2B3B
Histone H2B type 3-B

1

10

High-throughput

0.536

High

340366

CDYL2
Chromodomain Y-like protein 2

1

1

High-throughput

0.536

High

340372

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

3

High-throughput

0.536

High

340373

ING5
Inhibitor of growth protein 5

1

4

High-throughput

0.536

High

340394

KLF16
Krueppel-like factor 16

1

2

High-throughput

0.536

High

340398

NSD3
Histone-lysine N-methyltransferase NSD3

1

4

High-throughput

0.536

High

340414

DPOE3
DNA polymerase epsilon subunit 3

1

4

High-throughput

0.536

High

340334

H2B2E
Histone H2B type 2-E

1

10

High-throughput

0.515

High

186972

PPM1G
Protein phosphatase 1G

1

0

High-throughput

0.513

High

244060

ZN292
Zinc finger protein 292

1

0

High-throughput

0.513

High

326809

SPN1
Snurportin-1

1

0

High-throughput

0.513

High

340275

PTTG1
Securin

1

0

High-throughput

0.513

High

340290

PLAK
Junction plakoglobin

1

0

High-throughput

0.513

High

340341

ESCO2
N-acetyltransferase ESCO2

1

0

High-throughput

0.513

High

340361

ZN687
Zinc finger protein 687

1

0

High-throughput

0.513

High

340381

EME1
Structure-specific endonuclease subunit EME1

1

0

High-throughput

0.513

High

340395

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.513

High

340405

TSYL2
Testis-specific Y-encoded-like protein 2

1

0

High-throughput

0.513

High

340318

H31
Histone H3.1

1

9

Small-scale

0.501

High

340397

TRI54
Tripartite motif-containing protein 54

1

1

High-throughput

0.494

High

340297

ECHM
Enoyl-CoA hydratase, mitochondrial

1

1

High-throughput

0.489

High

340347

REEP3
Receptor expression-enhancing protein 3

1

1

High-throughput

0.489

High

340353

GRIN1
G protein-regulated inducer of neurite outgrowth 1

1

1

High-throughput

0.489

High

340367

POC1A
POC1 centriolar protein homolog A

1

8

High-throughput

0.489

High

340343

CE162
Centrosomal protein of 162 kDa

1

1

Small-scale

0.481

High

132689

BMAL1
Basic helix-loop-helix ARNT-like protein 1

1

1

High-throughput

0.479

High

172369

XPO1
Exportin-1

1

5

High-throughput

0.479

High

180641

TIF1A
Transcription intermediary factor 1-alpha

1

5

High-throughput

0.479

High

192893

CLOCK
Circadian locomoter output cycles protein kaput

1

1

High-throughput

0.479

High

340280

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

340282

LYN
Tyrosine-protein kinase Lyn

1

2

Small-scale

0.479

High

340293

CEBPB
CCAAT/enhancer-binding protein beta

1

3

High-throughput

0.479

High

340295

TYY1
Transcriptional repressor protein YY1

1

1

High-throughput

0.479

High

340296

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

340299

ELF1
ETS-related transcription factor Elf-1

1

1

High-throughput

0.479

High

340300

H2B1B
Histone H2B type 1-B

1

10

High-throughput

0.479

High

340304

HNF4A
Hepatocyte nuclear factor 4-alpha

1

6

High-throughput

0.479

High

340306

YAP1
Transcriptional coactivator YAP1

1

2

High-throughput

0.479

High

340314

H4
Histone H4

1

4

High-throughput

0.479

High

340319

PO5F1
POU domain, class 5, transcription factor 1

1

3

High-throughput

0.479

High

340323

SQSTM
Sequestosome-1

1

1

High-throughput

0.479

High

340325

NFIX
Nuclear factor 1 X-type

1

4

High-throughput

0.479

High

340329

BRD3
Bromodomain-containing protein 3

1

9

High-throughput

0.479

High

340331

STIL
SCL-interrupting locus protein

1

1

High-throughput

0.479

High

340333

H31T
Histone H3.1t

1

9

Small-scale

0.479

High

340335

GRAP1
GRIP1-associated protein 1

1

1

High-throughput

0.479

High

340356

HDGR2
Hepatoma-derived growth factor-related protein 2

1

2

High-throughput

0.479

High

340360

CCAR2
Cell cycle and apoptosis regulator protein 2

1

1

Small-scale

0.479

High

340377

ESR2
Estrogen receptor beta

1

7

High-throughput

0.479

High

340382

PF21A
PHD finger protein 21A

1

5

High-throughput

0.479

High

340391

KLF6
Krueppel-like factor 6

1

2

High-throughput

0.479

High

340399

NUF2
Kinetochore protein Nuf2

1

1

High-throughput

0.479

High

340402

WWTR1
WW domain-containing transcription regulator protein 1

1

2

High-throughput

0.479

High

340411

HM20A
High mobility group protein 20A

1

3

High-throughput

0.479

High

340425

RCOR1
REST corepressor 1

1

3

High-throughput

0.479

High

340316

ACTC
Actin, alpha cardiac muscle 1

1

3

High-throughput

0.470

High

302288

RNF8
E3 ubiquitin-protein ligase RNF8

1

0

Small-scale

0.460

High

128365

PSMD9
26S proteasome non-ATPase regulatory subunit 9

1

0

High-throughput

0.458

High

217032

MS18B
Protein Mis18-beta

1

0

High-throughput

0.458

High

340285

TFPT
TCF3 fusion partner

1

0

High-throughput

0.458

High

340313

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

340324

GIT2
ARF GTPase-activating protein GIT2

1

0

High-throughput

0.458

High

340328

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

340348

CAVN1
Caveolae-associated protein 1

1

0

High-throughput

0.458

High

340349

PKN3
Serine/threonine-protein kinase N3

1

0

High-throughput

0.458

High

340370

CCHCR
Coiled-coil alpha-helical rod protein 1

1

0

High-throughput

0.458

High

340385

THA11
THAP domain-containing protein 11

1

0

High-throughput

0.458

High

340389

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

0

High-throughput

0.458

High

340396

PDIP3
Polymerase delta-interacting protein 3

1

0

High-throughput

0.458

High

340400

REN3B
Regulator of nonsense transcripts 3B

1

0

High-throughput

0.458

High

340422

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

340426

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.458

High

95941

E7ET07
Inhibitor of growth protein

1

5

High-throughput

0.445

High

97294

E9PSF2
STIL centriolar assembly protein

1

1

High-throughput

0.445

High

340390

CDC5L
Cell division cycle 5-like protein

1

1

High-throughput

0.445

High

340417

SIR5
NAD-dependent protein deacylase sirtuin-5, mitochondrial

1

2

High-throughput

0.445

High

340427

TRI33
E3 ubiquitin-protein ligase TRIM33

1

5

Small-scale

0.445

High

340420

FRM4A
FERM domain-containing protein 4A

1

6

Small-scale

0.439

High

228533

STRN
Striatin

1

8

High-throughput

0.437

High

340338

EIPR1
EARP and GARP complex-interacting protein 1

1

7

High-throughput

0.437

High

340365

PTGR2
Prostaglandin reductase 2

1

1

High-throughput

0.437

High

340369

GOGA5
Golgin subfamily A member 5

1

1

High-throughput

0.437

High

340386

GRM2B
GRAM domain-containing protein 2B

1

1

High-throughput

0.437

High

340392

ATX2
Ataxin-2

1

1

High-throughput

0.437

High

71807

FOXO6
Forkhead box protein O6

1

0

High-throughput

0.426

High

340307

IMA5
Importin subunit alpha-5

1

0

High-throughput

0.426

High

340337

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.426

High

340393

AN32E
Acidic leucine-rich nuclear phosphoprotein 32 family member E

1

0

Small-scale

0.426

High

107363

F8W057
Actin-related protein 6

1

8

High-throughput

0.407

High

108068

G3V3Y1
15-oxoprostaglandin 13-reductase

1

1

High-throughput

0.407

High

114535

H0YH87
Ataxin 2

1

1

High-throughput

0.407

High

340380

RN166
E3 ubiquitin-protein ligase RNF166

1

1

High-throughput

0.407

High

340376

MY18A
Unconventional myosin-XVIIIa

3

0

High-throughput

0.347

High

340428

MTMR7
Phosphatidylinositol-3-phosphate phosphatase MTMR7

3

0

High-throughput

0.342

High

340294

TPH1
Tryptophan 5-hydroxylase 1

2

0

High-throughput

0.328

High

340355

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

2

0

High-throughput

0.328

High

340384

CSTOS
Protein CUSTOS

2

0

High-throughput

0.318

High

340416

FBX34
F-box only protein 34

2

0

High-throughput

0.318

High

340289

CX6B1
Cytochrome c oxidase subunit 6B1

1

0

High-throughput

0.279

Low

340342

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.279

Low

340364

MILK1
MICAL-like protein 1

1

0

High-throughput

0.279

Low

340371

CGAT1
Chondroitin sulfate N-acetylgalactosaminyltransferase 1

1

0

High-throughput

0.279

Low

340375

FIG4
Polyphosphoinositide phosphatase

1

0

High-throughput

0.279

Low

261749

PFD1
Prefoldin subunit 1

1

0

Small-scale

0.251

Low

85226

RBG10
Rab GTPase-activating protein 1-like, isoform 10

1

0

High-throughput

0.249

Low

340330

RABE1
Rab GTPase-binding effector protein 1

1

0

High-throughput

0.249

Low

340340

CCD93
Coiled-coil domain-containing protein 93

1

0

High-throughput

0.249

Low

340344

VPS53
Vacuolar protein sorting-associated protein 53 homolog

1

0

High-throughput

0.249

Low

340346

PHLB3
Pleckstrin homology-like domain family B member 3

1

0

High-throughput

0.249

Low

340354

HAUS6
HAUS augmin-like complex subunit 6

1

0

High-throughput

0.249

Low

340358

DZIP3
E3 ubiquitin-protein ligase DZIP3

1

0

High-throughput

0.249

Low

340387

VPS50
Syndetin

1

0

High-throughput

0.249

Low

340408

PLAC1
Placenta-specific protein 1

1

0

High-throughput

0.249

Low

340409

NCK5L
Nck-associated protein 5-like

1

0

High-throughput

0.249

Low

340410

TUFT1
Tuftelin

1

0

High-throughput

0.249

Low

340419

HECW2
E3 ubiquitin-protein ligase HECW2

1

0

High-throughput

0.249

Low

340423

VPS51
Vacuolar protein sorting-associated protein 51 homolog

1

0

High-throughput

0.249

Low

340424

RABX5
Rab5 GDP/GTP exchange factor

1

0

High-throughput

0.249

Low

340406

GOLP3
Golgi phosphoprotein 3

1

0

High-throughput

0.232

Low

340412

RAB18
Ras-related protein Rab-18

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025