HitPredict

Interactor 1: E9PJF5 (E9PJF5)
BRMS1 transcriptional repressor and anoikis regulator
Gene: BRMS1

Interactor 2: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0042826 - histone deacetylase binding GO:0070822 - Sin3-type complex
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 244 Hs			1 482
+	Hs
		1038732 BRMS1_HUMAN (1-244): 1.25e-91: 271: 100.00		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		1270456 BRMS1_HUMAN (1-244): 1.25e-91: 271: 100.00		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Mm
		140312 BRMS1_MOUSE (1-244): 8.76e-89: 264: 92.62		HDAC1_MOUSE (1-482): 0: 672: 99.38
+	Hs
		1038441 BRM1L_HUMAN (1-244): 1.01e-83: 254: 52.44		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		1129638 BRM1L_HUMAN (1-244): 1.01e-83: 254: 52.44		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		177386 BRMS1_HUMAN (1-244): 1.25e-91: 271: 100.00		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Hs
		1038717 SDS3_HUMAN (34-238): 1.17e-52: 175: 21.26		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		1270447 SDS3_HUMAN (34-238): 1.17e-52: 175: 21.26		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		1336545 BRMS1_HUMAN (1-244): 1.25e-91: 271: 100.00		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78