Protein: G5EFG1
PDZ and LIM domain protein Zasp

Gene: G5EFG1, alp-1
Organism: Caenorhabditis elegans
Interactions: 127
UniProt ID: G5EFG1

Gene Ontology (top 5):
GO:0001725 - stress fiber
GO:0003779 - actin binding
GO:0005912 - adherens junction
GO:0008340 - determination of adult lifespan
GO:0030018 - Z disc

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

113218

H2L2C8
Alpha-actinin, sarcomeric

3

20

High-throughput

0.825

High

113212

G5EFG1
PDZ and LIM domain protein Zasp

2

19

High-throughput

0.754

High

113301

Q95QI3
PDZ domain-containing protein

2

4

High-throughput

0.754

High

110410

G5EC35
Beta chain spectrin homolog Sma1

1

20

High-throughput

0.621

High

110748

G5ECD7
cGMP-dependent protein kinase interacting domain-containing protein

1

9

High-throughput

0.621

High

113259

PXL1
Paxillin homolog 1

1

20

High-throughput

0.621

High

113293

Q3S1I9
LIM zinc-binding domain-containing protein

1

19

Small-scale

0.618

High

113316

ILKH
Integrin-linked protein kinase homolog pat-4

1

12

Small-scale

0.618

High

111338

G5ED33
Epidermal growth factor receptor pathway substrate 8 splice variant A

2

19

High-throughput

0.584

High

113222

O02174
C3H1-type domain-containing protein

3

3

High-throughput

0.583

High

113262

CC130
Coiled-coil domain-containing protein 130 homolog

3

3

High-throughput

0.583

High

113264

MEK2
Dual specificity mitogen-activated protein kinase kinase mek-2

3

7

High-throughput

0.583

High

113272

YTE4
Uncharacterized protein C09G1.4

3

2

High-throughput

0.583

High

113280

Q20398
PDZ domain-containing protein

3

11

High-throughput

0.583

High

113283

Q20712
CLASP_N domain-containing protein

3

2

High-throughput

0.583

High

113311

Q9N4P3
R3H domain-containing protein

3

3

High-throughput

0.583

High

113213

BRC2
DNA repair protein brc-2

2

1

Small-scale

0.565

High

113274

Q18529
Chitin-binding type-2 domain-containing protein

2

1

High-throughput

0.565

High

113269

Q17525
TEStin

1

19

Small-scale

0.553

High

113257

ROCK
Rho-associated protein kinase let-502

1

4

Small-scale

0.552

High

113250

EF1A
Elongation factor 1-alpha

2

3

Small-scale

0.535

High

113225

O44490
ELKS/RAB6-interacting/CAST family member 2

2

9

High-throughput

0.533

High

95660

E3W743
ZM domain-containing protein

2

2

High-throughput

0.533

High

113216

H2KZP3
Uncharacterized protein

2

2

High-throughput

0.533

High

113231

O62486
Nanos-type domain-containing protein

2

2

High-throughput

0.533

High

113233

ABL1
Tyrosine-protein kinase abl-1

2

20

High-throughput

0.533

High

113248

ZTF17
Zinc finger transcription factor family protein 17

2

2

High-throughput

0.533

High

113288

RS7
Small ribosomal subunit protein eS7

2

1

High-throughput

0.533

High

113289

Q23458
C2H2-type domain-containing protein

2

1

High-throughput

0.533

High

113290

LI15A
Protein lin-15A

2

1

High-throughput

0.533

High

113300

PAT12
Protein pat-12

2

1

High-throughput

0.533

High

92473

D3YT29
PDZ domain-containing protein

1

10

High-throughput

0.481

High

109075

G4S034
Spectrin alpha chain

1

20

Small-scale

0.481

High

112295

SRC1
Tyrosine protein-kinase src-1

1

20

High-throughput

0.481

High

113230

SRC2
Tyrosine protein-kinase src-2

1

20

High-throughput

0.481

High

113246

UNC87
Protein unc-87

1

7

High-throughput

0.481

High

113247

MPK1
Mitogen-activated protein kinase mpk-1

1

6

High-throughput

0.481

High

113261

MLRH
Myosin regulatory light chain

1

8

Small-scale

0.481

High

113268

PAR3
Partitioning defective protein 3

1

13

High-throughput

0.481

High

113275

HSP90
Heat shock protein 90

1

2

High-throughput

0.481

High

113306

Q9BIC1
Afadin

1

12

High-throughput

0.481

High

113321

TYDP2
5'-tyrosyl-DNA phosphodiesterase

1

1

High-throughput

0.481

High

113236

ACT4
Actin-4

1

13

Small-scale

0.479

High

113242

PAT2
Integrin alpha pat-2

1

12

Small-scale

0.479

High

113281

Q20641
Myosin-11

1

5

Small-scale

0.479

High

113292

PAT3
Integrin beta pat-3

1

10

Small-scale

0.479

High

113313

RS6
Small ribosomal subunit protein eS6

1

0

Small-scale

0.458

High

64196

A5Z2V0
CID domain-containing protein

1

1

High-throughput

0.439

High

84468

B7WN95
60S ribosomal protein L32

1

1

High-throughput

0.439

High

90579

C1P629
RRM domain-containing protein

1

3

High-throughput

0.439

High

109730

G5EBP5
63 kDa sperm flagellar membrane protein

1

5

High-throughput

0.439

High

111614

G5EDA8
Chitin-binding type-2 domain-containing protein

1

1

High-throughput

0.439

High

112463

NFYA1
Nuclear transcription factor Y subunit nfya-1

1

2

High-throughput

0.439

High

113214

H2KZ17
DiSHevelled related

1

15

High-throughput

0.439

High

113215

H2KZN0
RRM domain-containing protein

1

5

High-throughput

0.439

High

113217

H2L2C3
Rap-GAP domain-containing protein

1

4

High-throughput

0.439

High

113219

H8W3X6
EF-hand domain-containing protein

1

4

High-throughput

0.439

High

113221

O01900
TFIIS central domain-containing protein

1

10

High-throughput

0.439

High

113223

O16286
PB1 domain-containing protein

1

1

High-throughput

0.439

High

113224

O16701
Kunitz/Bovine pancreatic trypsin inhibitor domain protein

1

7

High-throughput

0.439

High

113226

O44821
Ubiquitin-like domain-containing protein

1

5

High-throughput

0.439

High

113227

O45268
FAM65 N-terminal domain-containing protein

1

1

High-throughput

0.439

High

113228

O45334
CLaudin-like in Caenorhabditis

1

1

High-throughput

0.439

High

113229

NH111
Nuclear hormone receptor family member nhr-111

1

20

High-throughput

0.439

High

113232

O76572
SH2 domain-containing protein

1

3

High-throughput

0.439

High

113239

EIF3D
Eukaryotic translation initiation factor 3 subunit D

1

2

High-throughput

0.439

High

113241

NCOR1
Nuclear receptor corepressor 1

1

6

High-throughput

0.439

High

113243

ZTF1
Heterogeneous nuclear ribonucleoprotein C homolog

1

8

High-throughput

0.439

High

113244

NCL1
B-box type zinc finger protein ncl-1

1

20

High-throughput

0.439

High

113245

SC161
Protein transport protein sec-16A.1

1

5

High-throughput

0.439

High

113251

LIN2
Protein lin-2

1

2

High-throughput

0.439

High

113252

P91051
SKA2 domain-containing protein

1

1

High-throughput

0.439

High

113253

P91056
Ubiquitin-like domain-containing protein

1

1

High-throughput

0.439

High

113254

P91250
Nematode cuticle collagen N-terminal domain-containing protein

1

2

High-throughput

0.439

High

113255

P91306
CSD domain-containing protein

1

1

High-throughput

0.439

High

113256

RM24
Large ribosomal subunit protein uL24m

1

1

High-throughput

0.439

High

113258

MEX6
Zinc finger protein mex-6

1

3

High-throughput

0.439

High

113260

TX1B3
Tax1-binding protein 3 homolog

1

7

High-throughput

0.439

High

113263

GARS
Glycine--tRNA ligase

1

1

High-throughput

0.439

High

113265

RNP1
RNA-binding protein rnp-1

1

2

High-throughput

0.439

High

113266

Q10929
SH3 domain-containing protein

1

19

High-throughput

0.439

High

113267

YPC4
Uncharacterized protein C05D10.4

1

1

High-throughput

0.439

High

113270

Q17625
SCP domain-containing protein

1

1

High-throughput

0.439

High

113271

Q17732
SH2 domain-containing protein

1

1

High-throughput

0.439

High

113273

Q18241
Helicase ARIP4

1

1

High-throughput

0.439

High

113276

TOCA1
Transducer of Cdc42-dependent actin assembly protein 1 homolog

1

2

High-throughput

0.439

High

113277

YAP1
Yes-associated protein homolog 1

1

1

High-throughput

0.439

High

113278

Q19862
Transcription factor AP-2 C-terminal domain-containing protein

1

4

High-throughput

0.439

High

113279

SAS5
Spindle assembly abnormal protein 5

1

1

High-throughput

0.439

High

113282

Q20711
RNA-binding protein 6

1

1

High-throughput

0.439

High

113284

UNC84
Nuclear migration and anchoring protein unc-84

1

2

High-throughput

0.439

High

113285

Q20956
Spt4 domain-containing protein

1

2

High-throughput

0.439

High

113286

Q22459
Homeobox domain-containing protein

1

5

High-throughput

0.439

High

113287

Q22696
C2H2-type domain-containing protein

1

1

High-throughput

0.439

High

113294

Q6BEW1
Copper transport protein

1

1

High-throughput

0.439

High

113295

Q8I4L6
CUB-like domain-containing protein

1

1

High-throughput

0.439

High

113296

Q8ITW3
BZIP domain-containing protein

1

1

High-throughput

0.439

High

113297

Q8IU04
RING-type domain-containing protein

1

1

High-throughput

0.439

High

113298

Q8MXR2
RRM domain-containing protein

1

6

High-throughput

0.439

High

113299

YRGK
Uncharacterized protein D2005.3

1

1

High-throughput

0.439

High

113302

GLD3
Defective in germ line development protein 3

1

1

High-throughput

0.439

High

113303

Q965W3
Catechol O-methyltransferase domain-containing protein 1

1

1

High-throughput

0.439

High

113304

Q966J6
ZM domain-containing protein

1

1

High-throughput

0.439

High

113305

Q966J7
Leucine-rich repeat-containing protein DDB_G0290503

1

1

High-throughput

0.439

High

113307

Q9GUC8
IBR domain-containing protein

1

1

High-throughput

0.439

High

113308

Q9N312
Uncharacterized protein

1

1

High-throughput

0.439

High

113309

Q9N3Z0
ZZ-type domain-containing protein

1

13

High-throughput

0.439

High

113310

RL10A
Large ribosomal subunit protein uL1

1

1

High-throughput

0.439

High

113312

STAT1
Signal transducer and activator of transcription 1

1

4

High-throughput

0.439

High

113315

Q9TZ50
CCDC92/74 N-terminal domain-containing protein

1

1

High-throughput

0.439

High

113317

Q9U2U6
Sorting nexin-13

1

3

High-throughput

0.439

High

113318

Q9XU12
Kinesin-like protein

1

5

High-throughput

0.439

High

113319

RL8
Large ribosomal subunit protein uL2

1

1

High-throughput

0.439

High

113320

FLP19
FMRFamide-like neuropeptides 19 [Cleaved into: WANQVRF-amide]

1

1

High-throughput

0.439

High

113322

ANI3
Anillin-like protein 3

1

3

High-throughput

0.439

High

113323

Q9XWT3
Uterine Lumin Expressed/locailized

1

1

High-throughput

0.439

High

90653

C1P636
E1 ubiquitin-activating enzyme

1

1

Small-scale

0.437

High

113220

UNC89
Muscle M-line assembly protein unc-89

1

7

Small-scale

0.437

High

113234

ACT3
Actin-3

1

13

Small-scale

0.437

High

113235

ACT2
Actin-2

1

13

Small-scale

0.437

High

113237

MYO3
Myosin-3

1

4

Small-scale

0.437

High

113240

PLK1
Serine/threonine-protein kinase plk-1

1

6

High-throughput

0.437

High

113249

CH60
Chaperonin homolog Hsp-60, mitochondrial

1

1

Small-scale

0.437

High

113291

LI15B
Protein lin-15B

1

0

High-throughput

0.251

Low

113238

IF4A
Eukaryotic initiation factor 4A

1

0

Small-scale

0.249

Low

113314

Q9TXM1
Uncharacterized protein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025