HitPredict

Interactor 1: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Interactor 2: CREL2 (Q6UXH1)
Protein disulfide isomerase CRELD2 (EC 5.3.4.1) (Cysteine-rich with EGF-like domain protein 2)
Gene: CRELD2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.50	0.417

Property	Details
Experiments	21900206
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 353
+	Hs
		545674 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		TEN3_HUMAN (29-252): 4.1e-28: 117: 15.22
+	Hs
		254256 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		LRP4_HUMAN (18-351): 1.14e-23: 104: 13.15
+	Hs
		892650 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		TEN3_HUMAN (29-252): 4.1e-28: 117: 15.22
+	Hs
		894539 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		TEN3_HUMAN (29-252): 4.1e-28: 117: 15.22
+	Hs
		925280 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		FAT1_HUMAN (253-352): 5.36e-21: 96.8: 16.00
+	Hs
		564529 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		FAT1_HUMAN (253-352): 5.36e-21: 96.8: 16.00
+	Hs
		545377 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		FAT1_HUMAN (253-352): 5.36e-21: 96.8: 16.00
+	Hs
		1055012 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		FAT1_HUMAN (253-352): 5.36e-21: 96.8: 16.00
+	Hs
		892373 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		FAT1_HUMAN (253-352): 5.36e-21: 96.8: 16.00
+	Hs
		950997 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		FAT1_HUMAN (253-352): 5.36e-21: 96.8: 16.00
+	Hs
		894007 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		FAT1_HUMAN (253-352): 5.36e-21: 96.8: 16.00
+	Hs
		823033 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		AGRE5_HUMAN (259-353): 2.97e-09: 60.5: 21.43
+	Hs
		951084 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		TEN4_HUMAN (181-347): 6.45e-14: 75.2: 13.51
+	Hs
		823096 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		AGRE5_HUMAN (259-353): 2.97e-09: 60.5: 21.43
+	Hs
		892441 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		FAT4_HUMAN (23-103): 2.62e-09: 60.9: 12.05
+	Hs
		823027 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		AGRE5_HUMAN (259-353): 2.97e-09: 60.5: 21.43
+	Hs
		823035 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		AGRE5_HUMAN (259-353): 2.97e-09: 60.5: 21.43
+	Hs
		894146 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		FAT4_HUMAN (23-103): 2.62e-09: 60.9: 12.05
+	Hs
		823028 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		AGRE5_HUMAN (259-353): 2.97e-09: 60.5: 21.43
+	Hs
		823029 RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98		AGRE5_HUMAN (259-353): 2.97e-09: 60.5: 21.43