HitPredict

Interactor 1: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Interactor 2: C2CD5 (Q86YS7)
C2 domain-containing protein 5 (C2 domain-containing phosphoprotein of 138 kDa)
Gene: C2CD5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005938 - cell cortex GO:0032587 - ruffle membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 1000
+	Hs
		564599 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		C2CD5_HUMAN (1-1000): 0: 1612: 100.00
+	Hs
		545481 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		C2CD5_HUMAN (1-1000): 0: 1612: 100.00
+	Hs
		1205952 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		C2CD5_HUMAN (1-1000): 0: 1612: 100.00
+	Hs
		892470 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		C2CD5_HUMAN (1-1000): 0: 1612: 100.00
+	Hs
		951131 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		C2CD5_HUMAN (1-1000): 0: 1612: 100.00
+	Hs
		894187 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		C2CD5_HUMAN (1-1000): 0: 1612: 100.00
+	Hs
		900658 RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98		C2CD5_HUMAN (1-1000): 0: 1612: 100.00
+	Hs
		925568 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		ESYT1_HUMAN (7-116): 1.97e-11: 70.5: 21.19
+	Hs
		564663 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		ESYT1_HUMAN (7-116): 1.97e-11: 70.5: 21.19
+	Hs
		545587 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		ESYT1_HUMAN (7-116): 1.97e-11: 70.5: 21.19
+	Hs
		1311394 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		ESYT1_HUMAN (7-116): 1.97e-11: 70.5: 21.19
+	Hs
		892564 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		ESYT1_HUMAN (7-116): 1.97e-11: 70.5: 21.19
+	Hs
		951279 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		ESYT1_HUMAN (7-116): 1.97e-11: 70.5: 21.19
+	Hs
		894369 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		ESYT1_HUMAN (7-116): 1.97e-11: 70.5: 21.19
+	Hs
		900846 RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98		ESYT1_HUMAN (7-116): 1.97e-11: 70.5: 21.19
+	Hs
		436481 RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45		ESYT1_HUMAN (7-116): 1.97e-11: 70.5: 21.19