HitPredict

Interactor 1: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Interactor 2: AT133 (Q9H7F0)
Polyamine-transporting ATPase 13A3 (ATPase family homolog up-regulated in senescence cells 1) (Putrescine transporting ATPase) (EC 7.6.2.16)
Gene: ATP13A3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane GO:0055038 - recycling endosome membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 1226
+	Hs
		564688 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		AT133_HUMAN (1-1226): 0: 1057: 100.00
+	Hs
		545623 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		AT133_HUMAN (1-1226): 0: 1057: 100.00
+	Hs
		1330920 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		AT133_HUMAN (1-1226): 0: 1057: 100.00
+	Hs
		892600 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		AT133_HUMAN (1-1226): 0: 1057: 100.00
+	Hs
		951345 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		AT133_HUMAN (1-1226): 0: 1057: 100.00
+	Hs
		894438 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		AT133_HUMAN (1-1226): 0: 1057: 100.00
+	Hs
		900911 RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98		AT133_HUMAN (1-1226): 0: 1057: 100.00
+	Hs
		393152 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		AT1A1_HUMAN (151-1172): 0: 690: 18.99
+	Hs
		393020 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		AT1A1_HUMAN (151-1172): 0: 690: 18.99
+	Hs
		393014 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		AT1A1_HUMAN (151-1172): 0: 690: 18.99
+	Hs
		530865 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		AT1A3_HUMAN (151-1172): 0: 680: 17.78
+	Hs
		393348 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		AT1A1_HUMAN (151-1172): 0: 690: 18.99
+	Hs
		393129 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		AT1A1_HUMAN (151-1172): 0: 690: 18.99
+	Hs
		393158 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		AT1A1_HUMAN (151-1172): 0: 690: 18.99
+	Hs
		393131 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		AT1A1_HUMAN (151-1172): 0: 690: 18.99
+	Hs
		393135 RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98		AT1A1_HUMAN (151-1172): 0: 690: 18.99
+	Hs
		925638 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		AT131_HUMAN (26-1175): 0: 623: 22.23
+	Hs
		900933 RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98		AT131_HUMAN (26-1175): 0: 623: 22.23
+	Hs
		561551 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		AT2A2_HUMAN (279-1012): 1.69e-21: 103: 23.39
+	Hs
		561542 RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98		AT2A2_HUMAN (279-1012): 1.69e-21: 103: 23.39