HitPredict

Interactor 1: AP2B1 (P63010)
AP-2 complex subunit beta (AP105B) (Adaptor protein complex AP-2 subunit beta) (Adaptor-related protein complex 2 subunit beta) (Beta-2-adaptin) (Beta-adaptin) (Clathrin assembly protein complex 2 beta large chain) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit)
Gene: AP2B1

Interactor 2: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28877994
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 937 Hs			1 1121
+	Hs
		1014032 AP1B1_HUMAN (1-937): 0: 888: 82.72		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		321570 AP2A1_HUMAN (11-932): 0: 634: 16.97		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		302172 AP2A2_HUMAN (11-933): 0: 600: 16.99		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		925943 AP2B1_HUMAN (1-937): 0: 926: 100.00		RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32
+	Hs
		212634 AP1G1_HUMAN (11-808): 1.03e-173: 527: 17.57		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		926010 AP2B1_HUMAN (1-937): 0: 926: 100.00		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		1014047 AP1B1_HUMAN (1-937): 0: 888: 82.72		RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32
+	Hs
		1014080 AP1B1_HUMAN (1-937): 0: 888: 82.72		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		321639 AP2A1_HUMAN (11-932): 0: 634: 16.97		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		302207 AP2A2_HUMAN (11-933): 0: 600: 16.99		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		863267 COPB_HUMAN (8-927): 0: 561: 12.47		RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32
+	Hs
		119996 AP3B1_HUMAN (8-594): 5.76e-178: 547: 28.17		RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32
+	Hs
		212645 AP1G1_HUMAN (11-808): 1.03e-173: 527: 17.57		RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32
+	Hs
		863332 COPB_HUMAN (8-927): 0: 561: 12.47		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		120033 AP3B1_HUMAN (8-594): 5.76e-178: 547: 28.17		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		1032737 AP3B2_HUMAN (16-594): 2.55e-174: 537: 28.71		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		1331763 AP4B1_HUMAN (15-628): 3.34e-176: 530: 29.63		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		212665 AP1G1_HUMAN (11-808): 1.03e-173: 527: 17.57		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		863355 COPB_HUMAN (8-927): 0: 561: 12.47		WWOX_HUMAN (9-115): 8.02e-20: 95.4: 29.91
+	Hs
		276359 AP1G2_HUMAN (11-698): 4e-162: 496: 14.73		NEDD4_HUMAN (11-95): 1.03e-15: 84.6: 24.17