HitPredict

Interactor 1: E9PMD8 (E9PMD8)
Proteasome 26S subunit, ATPase 3
Gene: PSMC3

Interactor 2: PSD11 (O00231)
26S proteasome non-ATPase regulatory subunit 11 (26S proteasome regulatory subunit RPN6) (26S proteasome regulatory subunit S9) (26S proteasome regulatory subunit p44.5)
Gene: PSMD11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 301 Hs			1 422
+	Hs
		121676 PRS6A_HUMAN (20-301): 6.23e-77: 242: 95.47		PSD11_HUMAN (1-422): 1.54e-117: 351: 100.00
+	Dm
		820482 PRS4_DROME (51-301): 1.04e-87: 270: 40.00		PSD11_DROME (4-422): 6.96e-107: 323: 67.46
+	Hs
		121703 PRS6B_HUMAN (9-301): 2.8e-68: 220: 34.13		PSD11_HUMAN (1-422): 1.54e-117: 351: 100.00
+	Dm
		1180706 Q7KMQ0_DROME (14-300): 2.08e-78: 246: 31.36		PSD11_DROME (4-422): 6.96e-107: 323: 67.46
+	Dm
		1180714 Q9V3V6_DROME (34-301): 1.89e-71: 228: 85.82		PSD11_DROME (4-422): 6.96e-107: 323: 67.46
+	Dm
		1180716 Q9V405_DROME (15-301): 4.18e-69: 222: 33.10		PSD11_DROME (4-422): 6.96e-107: 323: 67.46
+	At
		1338955 PS6AA_ARATH (37-301): 8.82e-71: 226: 76.69		PSD11_ARATH (10-421): 4.55e-96: 295: 51.94
+	Hs
		572913 PRS6A_HUMAN (20-301): 6.23e-77: 242: 95.47		CSN2_HUMAN (8-419): 1.5e-88: 277: 22.80
+	Dm
		820500 PRS4_DROME (51-301): 1.04e-87: 270: 40.00		PSMD6_DROME (31-422): 3.38e-72: 233: 13.93
+	Hs
		92622 E9PMD8_HUMAN (1-301): 1.14e-82: 253: 100.00		PSMD6_HUMAN (31-422): 3.57e-77: 246: 13.68
+	Hs
		572957 PRS6A_HUMAN (20-301): 6.23e-77: 242: 95.47		PSMD6_HUMAN (31-422): 3.57e-77: 246: 13.68
+	Sc
		703867 PRS6B_YEAST (13-301): 5.65e-71: 227: 32.19		RPN6_YEAST (39-421): 4.48e-81: 257: 45.36
+	Dm
		820499 PRS4_DROME (51-301): 1.04e-87: 270: 40.00		CSN4_DROME (36-421): 1.46e-64: 214: 11.88
+	Sc
		703763 PRS6A_YEAST (24-301): 1.52e-69: 223: 65.85		RPN6_YEAST (39-421): 4.48e-81: 257: 45.36
+	Hs
		92596 E9PMD8_HUMAN (1-301): 1.14e-82: 253: 100.00		PSD12_HUMAN (46-422): 1.57e-66: 220: 12.86
+	Hs
		798666 PRS6B_HUMAN (9-301): 2.8e-68: 220: 34.13		PSMD6_HUMAN (31-422): 3.57e-77: 246: 13.68
+	Hs
		121928 PRS6A_HUMAN (20-301): 6.23e-77: 242: 95.47		PSD12_HUMAN (46-422): 1.57e-66: 220: 12.86
+	Dm
		1358523 Q9V3V6_DROME (34-301): 1.89e-71: 228: 85.82		PSMD6_DROME (31-422): 3.38e-72: 233: 13.93
+	Dm
		1358526 Q9V405_DROME (15-301): 4.18e-69: 222: 33.10		PSMD6_DROME (31-422): 3.38e-72: 233: 13.93
+	Hs
		121959 PRS6B_HUMAN (9-301): 2.8e-68: 220: 34.13		PSD12_HUMAN (46-422): 1.57e-66: 220: 12.86