Interactor 1: VAMP2 (P63027)
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Gene: VAMP2
Interactor 2: STX4 (Q12846)
Syntaxin-4 (Renal carcinoma antigen NY-REN-31)
Gene: STX4
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.973 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 30217970, 29360461, 12517971, 8760387, 25416956, 32296183, 10820264, 34079125, 10194441, unassigned1304 |
| Identification Methods | two hybrid, affinity chromatography technology, proximity labelling technology, validated two hybrid, two hybrid prey pooling approach, two hybrid array |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | SNARE~Synaptobrevin, Synaptobrevin~Syntaxin |
| Common GO terms | GO:0000149 - SNARE binding GO:0005484 - SNAP receptor activity GO:0005802 - trans-Golgi network GO:0005829 - cytosol GO:0005886 - plasma membrane and 10 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
