HitPredict

Interactor 1: VAMP2 (P63027)
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Gene: VAMP2

Interactor 2: VAMP3 (Q15836)
Vesicle-associated membrane protein 3 (VAMP-3) (Cellubrevin) (CEB) (Synaptobrevin-3)
Gene: VAMP3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.799

The method score is based on:

Property Details
Experiments 12130530, 35271311
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Synaptobrevin~Synaptobrevin
Common GO terms GO:0005484 - SNAP receptor activity
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006887 - exocytosis
GO:0006906 - vesicle fusion
and 16 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 116
Hs

1 100
+ Dm
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+ Dm
+ Dm
+ Hs
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+ Sc
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+ Rn
+ Hs
+ Sc
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024