Interactor 1: IF4E (P63073)
Eukaryotic translation initiation factor 4E (eIF-4E) (eIF4E) (mRNA cap-binding protein) (eIF-4F 25 kDa subunit)
Gene: Eif4e
Interactor 2: 4EBP1 (Q60876)
Eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1) (eIF4E-binding protein 1) (Phosphorylated heat- and acid-stable protein regulated by insulin 1) (PHAS-I)
Gene: Eif4ebp1
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.973 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 20971826, 19209957, 18955708, 16760336, 15094042, 16990847, 16702305, 16166632, 8599949, 9211946, 15845920, 17689282 |
| Identification Methods | affinity chromatography technology, pull down, anti tag coimmunoprecipitation, two hybrid, far western blotting |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | IF4E~eIF_4EBP |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0032991 - protein-containing complex GO:0071549 - cellular response to dexamethasone stimulus and 2 others more... |
| Homologous interactions | 15 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
