HitPredict

Interactor 1: 1433Z (P63101)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1) (SEZ-2)
Gene: Ywhaz

Interactor 2: SIK3 (Q6P4S6)
Serine/threonine-protein kinase SIK3 (EC 2.7.11.1) (Salt-inducible kinase 3) (SIK-3) (Serine/threonine-protein kinase QSK)
Gene: SIK3

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16959763
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0006468 - protein phosphorylation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Mm			1 1369
+	Hs
		927683 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		SIK3_HUMAN (25-1369): 0: 1393: 87.97
+	Mm
		926780 1433Z_MOUSE (1-245): 3.48e-145: 407: 100.00		MARK3_MOUSE (12-753): 2.84e-159: 499: 28.99
+	Hs
		647869 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		MARK3_HUMAN (12-753): 7.13e-159: 498: 28.86
+	Mm
		910231 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		MARK3_MOUSE (12-753): 2.84e-159: 499: 28.99
+	Hs
		647862 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		MARK3_HUMAN (12-753): 7.13e-159: 498: 28.86
+	Hs
		927511 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		SIK2_HUMAN (48-1014): 1.08e-148: 477: 32.61
+	Hs
		927214 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		MARK2_HUMAN (9-753): 2.61e-147: 468: 29.01
+	Hs
		909730 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		MARK2_HUMAN (9-753): 2.61e-147: 468: 29.01
+	Mm
		910234 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		MARK2_MOUSE (9-748): 7.24e-144: 459: 29.27
+	Mm
		910308 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		MARK4_MOUSE (7-685): 3.98e-143: 456: 32.32
+	Hs
		927411 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		MARK4_HUMAN (7-687): 3.11e-142: 454: 32.85
+	Hs
		883215 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		SIK1_HUMAN (44-421): 1.11e-138: 445: 51.71
+	Hs
		883214 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		SIK1_HUMAN (44-421): 1.11e-138: 445: 51.71
+	Mm
		910318 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		MARK1_MOUSE (40-458): 1.76e-134: 434: 47.47
+	Hs
		927600 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		MARK1_HUMAN (40-458): 9.66e-133: 430: 46.31
+	Hs
		871356 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		AAPK2_HUMAN (52-414): 2.07e-132: 420: 38.90
+	Hs
		871354 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		AAPK2_HUMAN (52-414): 2.07e-132: 420: 38.90
+	Hs
		909590 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		KS6A2_HUMAN (4-317): 4.71e-105: 352: 30.89
+	Mm
		910272 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		BRSK2_MOUSE (60-398): 6.34e-77: 273: 42.82
+	Hs
		909786 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		BRSK2_HUMAN (60-398): 8.94e-77: 272: 42.82