HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: LCP2 (Q13094)
Lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76 kDa) (SLP-76 tyrosine phosphoprotein) (SLP76)
Gene: LCP2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.576

Property	Details
Experiments	20936779, 17353368
Identification Methods	two hybrid, coimmunoprecipitation
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 533
+	Hs
		909504 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		LCP2_HUMAN (1-533): 1.59e-78: 258: 100.00
+	Mm
		926796 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		LCP2_MOUSE (1-531): 8.21e-72: 240: 80.98
+	Mm
		910251 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		LCP2_MOUSE (1-531): 8.21e-72: 240: 80.98
+	Mm
		933124 1433T_MOUSE (1-245): 8.98e-140: 393: 79.18		LCP2_MOUSE (1-531): 8.21e-72: 240: 80.98
+	Mm
		905340 1433G_MOUSE (1-240): 2.37e-108: 314: 74.59		LCP2_MOUSE (1-531): 8.21e-72: 240: 80.98
+	Mm
		222320 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		O54737_MOUSE (52-523): 4.71e-33: 134: 19.88
+	Hs
		909666 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		TENS2_HUMAN (79-512): 3.43e-30: 127: 17.32
+	Hs
		297824 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		K0754_HUMAN (18-469): 5.29e-28: 121: 11.97
+	Hs
		297821 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		K0754_HUMAN (18-469): 5.29e-28: 121: 11.97
+	Hs
		683431 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		TENS2_HUMAN (79-512): 3.43e-30: 127: 17.32
+	Hs
		646992 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		TENS3_HUMAN (83-512): 1.87e-28: 122: 12.50
+	Hs
		683433 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		TENS3_HUMAN (83-512): 1.87e-28: 122: 12.50
+	Hs
		297815 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		K0754_HUMAN (18-469): 5.29e-28: 121: 11.97
+	Hs
		927549 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		TENS1_HUMAN (85-512): 1.44e-22: 104: 14.61
+	Hs
		927352 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		TITIN_HUMAN (174-447): 1.53e-11: 69.6: 10.64
+	Hs
		647151 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		TITIN_HUMAN (174-447): 1.53e-11: 69.6: 10.64
+	Hs
		647427 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		CABIN_HUMAN (65-320): 5.73e-09: 61.1: 11.92
+	Hs
		904698 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		TENS2_HUMAN (79-512): 3.43e-30: 127: 17.32
+	Hs
		904702 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		TENS3_HUMAN (83-512): 1.87e-28: 122: 12.50
+	Hs
		203217 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		SYNJ1_HUMAN (10-466): 1.18e-22: 104: 11.71