HitPredict

Interactor 1: ATX1 (P54253)
Ataxin-1 (Spinocerebellar ataxia type 1 protein)
Gene: ATXN1

Interactor 2: RHXF2 (Q9BQY4)
Rhox homeobox family member 2 (Paired-like homeobox protein PEPP-2) (Testis homeobox gene 1)
Gene: RHOXF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

Property	Details
Experiments	16713569, 32814053
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array, two hybrid pooling approach, validated two hybrid, luminescence based mammalian interactome mapping
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 815 Hs			1 288
+	Hs
		895696 ATX1_HUMAN (1-815): 0: 1349: 100.00		LHX2_HUMAN (67-271): 3.65e-32: 124: 13.17
+	Hs
		662209 ATX1_HUMAN (1-815): 0: 1349: 100.00		PAX7_HUMAN (117-288): 3.12e-31: 123: 21.02
+	Hs
		685135 ATX1_HUMAN (1-815): 0: 1349: 100.00		PAX6_HUMAN (64-280): 1.35e-30: 120: 22.12
+	Hs
		927203 ATX1_HUMAN (1-815): 0: 1349: 100.00		GSC_HUMAN (2-217): 5.73e-32: 120: 16.52
+	Mm
		205393 ATX1_MOUSE (1-815): 0: 1271: 86.89		PHX2B_MOUSE (92-194): 3.99e-37: 135: 33.98
+	Hs
		505515 ATX1L_HUMAN (1-815): 3.56e-108: 348: 27.15		PAX7_HUMAN (117-288): 3.12e-31: 123: 21.02
+	Hs
		505518 ATX1L_HUMAN (1-815): 3.56e-108: 348: 27.15		PAX6_HUMAN (64-280): 1.35e-30: 120: 22.12
+	Hs
		505540 ATX1L_HUMAN (1-815): 3.56e-108: 348: 27.15		GSC_HUMAN (2-217): 5.73e-32: 120: 16.52
+	Dm
		1489792 Q9W3V7_DROME (574-685): 5.42e-60: 205: 44.64		Q9W2P8_DROME (141-194): 1.42e-09: 60.1: 48.15