HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: PKHA2 (Q9HB19)
Pleckstrin homology domain-containing family A member 2 (PH domain-containing family A member 2) (Tandem PH domain-containing protein 2) (TAPP-2)
Gene: PLEKHA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	35271311, 36931259
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 425
+	Hs
		910041 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PKHA2_HUMAN (1-425): 2.61e-152: 439: 100.00
+	Hs
		927548 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PKHA1_HUMAN (1-425): 7.64e-108: 325: 44.21
+	Hs
		910043 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PKHA1_HUMAN (1-425): 7.64e-108: 325: 44.21
+	Mm
		926821 1433Z_MOUSE (1-245): 3.48e-145: 407: 99.59		MTMR5_MOUSE (3-298): 3.99e-48: 178: 16.93
+	Hs
		309464 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		MTMR5_HUMAN (3-298): 4.14e-49: 181: 17.56
+	Hs
		927168 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PKHA7_HUMAN (118-420): 6.77e-39: 151: 16.81
+	Hs
		909830 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		DP13B_HUMAN (91-418): 1.55e-39: 152: 13.21
+	Hs
		909680 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PKHA7_HUMAN (118-420): 6.77e-39: 151: 16.81
+	Hs
		927545 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PKHA5_HUMAN (118-392): 3.97e-37: 146: 15.05
+	Hs
		910040 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PKHA5_HUMAN (118-392): 3.97e-37: 146: 15.05
+	Hs
		909582 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ACAP2_HUMAN (15-361): 3.99e-37: 145: 16.00
+	Hs
		927202 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PKHM3_HUMAN (12-305): 4.88e-35: 139: 14.82
+	At
		965340 14332_ARATH (3-239): 6.89e-143: 401: 65.15		DRP2B_ARATH (56-317): 2.92e-36: 143: 17.63
+	Hs
		909720 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PKHM3_HUMAN (12-305): 4.88e-35: 139: 14.82
+	Mm
		910229 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		MPRIP_MOUSE (119-388): 8.39e-35: 139: 14.80
+	Hs
		927189 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		MPRIP_HUMAN (110-388): 7.33e-34: 136: 15.09
+	Hs
		909703 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		MPRIP_HUMAN (110-388): 7.33e-34: 136: 15.09
+	Mm
		910223 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		CYH2_MOUSE (134-322): 2.53e-34: 133: 21.50
+	Hs
		927353 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		ARAP2_HUMAN (185-326): 3.94e-12: 70.4: 18.18
+	Hs
		909866 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ARAP2_HUMAN (185-326): 3.94e-12: 70.4: 18.18