HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: CYLD (Q9NQC7)
Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD)
Gene: CYLD

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.671

Property	Details
Experiments	27591049, 35271311, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0019901 - protein kinase binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 956
+	Hs
		910060 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		647304 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		683740 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		905148 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		982530 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		684342 1433S_HUMAN (1-237): 8.27e-104: 302: 71.97		CYLD_HUMAN (1-956): 0: 1872: 100.00