Protein: RAC1
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (p21-Rac1)

Gene: RAC1
Organism: Mus musculus
Interactions: 64
UniProt ID: P63001

Gene Ontology (top 5):
GO:0000242 - pericentriolar material
GO:0001764 - neuron migration
GO:0001891 - phagocytic cup
GO:0001934 - positive regulation of protein phosphorylation
GO:0002093 - auditory receptor cell morphogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

109225

G5E884
non-specific serine/threonine protein kinase

4

20

Small-scale

0.878

High

988891

DLG4
Disks large homolog 4

3

20

High-throughput

0.847

High

988884

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

2

16

High-throughput

0.789

High

988885

RHG01
Rho GTPase-activating protein 1

1

20

Small-scale

0.692

High

988900

RHG22
Rho GTPase-activating protein 22

1

20

Small-scale

0.692

High

988877

TNIK
Traf2 and NCK-interacting protein kinase

1

20

High-throughput

0.691

High

988894

CYFP1
Cytoplasmic FMR1-interacting protein 1

1

17

High-throughput

0.691

High

988901

PK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

1

20

Small-scale

0.665

High

988897

RHG32
Rho GTPase-activating protein 32

1

20

Small-scale

0.647

High

312740

PAK1
Serine/threonine-protein kinase PAK 1

1

20

Small-scale

0.618

High

686947

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

20

Small-scale

0.618

High

878598

CTRO
Citron Rho-interacting kinase

1

20

Small-scale

0.618

High

988886

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

9

Small-scale

0.618

High

988887

ABR
Active breakpoint cluster region-related protein

1

20

Small-scale

0.618

High

988889

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

20

Small-scale

0.618

High

988892

BCR
Breakpoint cluster region protein

1

20

Small-scale

0.618

High

988893

NEB2
Neurabin-2

1

20

High-throughput

0.618

High

988896

CHIO
Beta-chimaerin

1

20

Small-scale

0.618

High

988902

DOCK1
Dedicator of cytokinesis protein 1

1

20

Small-scale

0.618

High

988904

PAK2
Serine/threonine-protein kinase PAK 2

1

20

Small-scale

0.618

High

988905

FNDC5
Fibronectin type III domain-containing protein 5

1

2

High-throughput

0.618

High

988911

GDIR1
Rho GDP-dissociation inhibitor 1

1

20

Small-scale

0.618

High

988916

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

20

Small-scale

0.618

High

988912

DLGP1
Disks large-associated protein 1

2

1

High-throughput

0.611

High

266872

E41L2
Band 4.1-like protein 2

1

20

High-throughput

0.590

High

312772

RAD
GTP-binding protein RAD

1

20

High-throughput

0.590

High

953795

CDC42
Cell division control protein 42 homolog

1

17

High-throughput

0.590

High

988878

EVI5
Ecotropic viral integration site 5 protein

1

15

High-throughput

0.590

High

988918

RHOA
Transforming protein RhoA

1

16

High-throughput

0.590

High

988876

TRAF6
TNF receptor-associated factor 6

1

15

Small-scale

0.578

High

988880

CTNB1
Catenin beta-1

1

20

Small-scale

0.575

High

988908

MK08
Mitogen-activated protein kinase 8

1

7

Small-scale

0.575

High

988920

MK09
Mitogen-activated protein kinase 9

1

7

Small-scale

0.575

High

704274

NCKP1
Nck-associated protein 1

1

4

High-throughput

0.536

High

771449

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

4

High-throughput

0.536

High

988913

TSC1
Hamartin

1

20

High-throughput

0.536

High

988888

Q5U3L0
SH3 domain-binding protein 2

1

0

Small-scale

0.517

High

59024

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

20

Small-scale

0.515

High

988881

APLP2
Amyloid beta precursor like protein 2

1

3

Small-scale

0.515

High

988909

EED
Polycomb protein EED

1

6

High-throughput

0.515

High

509019

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

1

12

Small-scale

0.501

High

108597

G3X9H5
Huntingtin

1

4

High-throughput

0.479

High

467752

SODC
Superoxide dismutase [Cu-Zn]

1

4

Small-scale

0.479

High

713193

NOS2
Nitric oxide synthase, inducible

1

10

Small-scale

0.479

High

890920

CAV1
Caveolin-1

1

10

Small-scale

0.479

High

965977

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

3

High-throughput

0.479

High

988879

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

4

High-throughput

0.479

High

988883

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

11

High-throughput

0.479

High

988890

XIAP
E3 ubiquitin-protein ligase XIAP

1

11

Small-scale

0.479

High

988895

FACD2
Fanconi anemia group D2 protein homolog

1

6

High-throughput

0.479

High

988898

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

8

High-throughput

0.479

High

988899

RCC2
Protein RCC2

1

4

Small-scale

0.479

High

988914

RBCC1
RB1-inducible coiled-coil protein 1

1

20

Small-scale

0.479

High

988919

HOME2
Homer protein homolog 2

1

20

Small-scale

0.479

High

237411

SGMR1
Sigma non-opioid intracellular receptor 1

1

0

Small-scale

0.458

High

927681

ATX1
Ataxin-1

1

0

High-throughput

0.458

High

988882

TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein

1

0

Small-scale

0.458

High

988915

AKIP1
A-kinase-interacting protein 1

1

0

Small-scale

0.458

High

988917

Q9JM08
Histone deacetylase

1

0

Small-scale

0.458

High

988910

NONO
Non-POU domain-containing octamer-binding protein

1

3

High-throughput

0.457

High

398287

CFAD
Complement factor D

1

3

High-throughput

0.437

High

988906

MAVS
Mitochondrial antiviral-signaling protein

1

20

Small-scale

0.437

High

988903

LTBP1
Latent-transforming growth factor beta-binding protein 1

1

20

High-throughput

0.417

High

988907

RBM39
RNA-binding protein 39

1

11

High-throughput

0.417

High


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Last updated: 11Aug2025