HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: FA53C (Q9NYF3)
Protein FAM53C
Gene: FAM53C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.723

Property	Details
Experiments	28514442, 33961781, 35271311, 36931259, 20936779
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 392
+	Hs
		1348464 V9HW98_HUMAN (2-241): 9.9e-144: 403: 68.18		FA53C_HUMAN (1-392): 1.07e-180: 509: 100.00
+	Hs
		910090 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		FA53C_HUMAN (1-392): 1.07e-180: 509: 100.00
+	Hs
		647325 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		FA53C_HUMAN (1-392): 1.07e-180: 509: 100.00
+	Hs
		683760 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		FA53C_HUMAN (1-392): 1.07e-180: 509: 100.00
+	Hs
		905181 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		FA53C_HUMAN (1-392): 1.07e-180: 509: 100.00
+	Hs
		982551 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		FA53C_HUMAN (1-392): 1.07e-180: 509: 100.00
+	Hs
		684357 1433S_HUMAN (1-237): 8.27e-104: 302: 71.97		FA53C_HUMAN (1-392): 1.07e-180: 509: 100.00
+	Hs
		927033 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		FA53B_HUMAN (1-392): 2.43e-90: 280: 27.63
+	Hs
		909550 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		FA53B_HUMAN (1-392): 2.43e-90: 280: 27.63
+	Hs
		646880 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		FA53B_HUMAN (1-392): 2.43e-90: 280: 27.63
+	Hs
		683338 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		FA53B_HUMAN (1-392): 2.43e-90: 280: 27.63
+	Hs
		904550 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		FA53B_HUMAN (1-392): 2.43e-90: 280: 27.63
+	Hs
		982001 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		FA53B_HUMAN (1-392): 2.43e-90: 280: 27.63
+	Hs
		684029 1433S_HUMAN (1-237): 8.27e-104: 302: 71.97		FA53B_HUMAN (1-392): 2.43e-90: 280: 27.63