HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: TAB2 (Q9NYJ8)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2)
Gene: TAB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	36931259, 21988832
Identification Methods	proximity labelling technology, two hybrid, two hybrid array
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 693
+	Hs
		910093 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		TAB2_HUMAN (1-693): 1.25e-111: 354: 100.00
+	Hs
		647327 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		TAB2_HUMAN (1-693): 1.25e-111: 354: 100.00
+	Hs
		927303 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		TAB3_HUMAN (1-692): 2.31e-70: 245: 29.77
+	Hs
		909812 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		TAB3_HUMAN (1-692): 2.31e-70: 245: 29.77
+	Hs
		647106 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		TAB3_HUMAN (1-692): 2.31e-70: 245: 29.77
+	Hs
		927241 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PHLB1_HUMAN (44-596): 6.26e-34: 141: 14.08
+	Hs
		909755 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		PHLB1_HUMAN (44-596): 6.26e-34: 141: 14.08
+	Hs
		647062 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		PHLB1_HUMAN (44-596): 6.26e-34: 141: 14.08
+	Hs
		297824 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		K0754_HUMAN (24-414): 1.17e-27: 122: 10.30
+	Hs
		297821 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		K0754_HUMAN (24-414): 1.17e-27: 122: 10.30
+	Hs
		297815 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		K0754_HUMAN (24-414): 1.17e-27: 122: 10.30
+	Hs
		927196 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		OTOG_HUMAN (25-588): 4.07e-22: 104: 10.14
+	Hs
		909712 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		OTOG_HUMAN (25-588): 4.07e-22: 104: 10.14
+	Hs
		926951 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		IF4G1_HUMAN (71-521): 3.73e-21: 101: 8.28
+	Hs
		647025 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		OTOG_HUMAN (25-588): 4.07e-22: 104: 10.14
+	Hs
		257597 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		ANR17_HUMAN (117-519): 7.6e-10: 64.7: 11.54
+	Hs
		257595 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ANR17_HUMAN (117-519): 7.6e-10: 64.7: 11.54
+	Hs
		846916 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81
+	Hs
		257566 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		ANR17_HUMAN (117-519): 7.6e-10: 64.7: 11.54
+	Hs
		257572 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		ANR17_HUMAN (117-519): 7.6e-10: 64.7: 11.54