HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: TBCD7 (Q9P0N9)
TBC1 domain family member 7 (Cell migration-inducing protein 23)
Gene: TBC1D7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

Property	Details
Experiments	30143532, 35271311
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:1904262 - negative regulation of TORC1 signaling
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 293
+	Hs
		910107 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		TBCD7_HUMAN (1-293): 0: 503: 100.00
+	Mm
		910332 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		TBCD7_MOUSE (1-293): 0: 501: 90.79
+	Hs
		683770 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		TBCD7_HUMAN (1-293): 0: 503: 100.00
+	Hs
		905196 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		TBCD7_HUMAN (1-293): 0: 503: 100.00
+	Hs
		982564 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		TBCD7_HUMAN (1-293): 0: 503: 100.00