HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: ERRFI (Q9UJM3)
ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (MIG-6)
Gene: ERRFI1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	24189400, 28842482, 35271311, 15778465
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 462
+	Hs
		910134 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ERRFI_HUMAN (1-462): 3.47e-85: 270: 100.00
+	Hs
		647364 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		ERRFI_HUMAN (1-462): 3.47e-85: 270: 100.00
+	Hs
		683799 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		ERRFI_HUMAN (1-462): 3.47e-85: 270: 100.00
+	Rn
		402804 1433T_RAT (1-245): 8.98e-140: 393: 79.18		ERRFI_RAT (1-462): 1.53e-76: 248: 82.47
+	Hs
		926964 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		ACK1_HUMAN (2-418): 1.43e-53: 195: 26.24
+	Hs
		927565 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		KI13B_HUMAN (24-375): 1.01e-21: 101: 15.14
+	Hs
		910062 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		KI13B_HUMAN (24-375): 1.01e-21: 101: 15.14
+	Hs
		257597 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		ANR17_HUMAN (83-378): 5.98e-21: 98.7: 12.67
+	Hs
		257595 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ANR17_HUMAN (83-378): 5.98e-21: 98.7: 12.67
+	Hs
		297824 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		K0754_HUMAN (38-315): 5.33e-20: 95.7: 10.07
+	Hs
		297821 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		K0754_HUMAN (38-315): 5.33e-20: 95.7: 10.07
+	Hs
		647306 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		KI13B_HUMAN (24-375): 1.01e-21: 101: 15.14
+	Hs
		683742 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		KI13B_HUMAN (24-375): 1.01e-21: 101: 15.14
+	Hs
		257566 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		ANR17_HUMAN (83-378): 5.98e-21: 98.7: 12.67
+	Hs
		257572 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		ANR17_HUMAN (83-378): 5.98e-21: 98.7: 12.67
+	Hs
		297815 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		K0754_HUMAN (38-315): 5.33e-20: 95.7: 10.07
+	Hs
		927196 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		OTOG_HUMAN (48-397): 3.72e-12: 71: 13.21
+	Hs
		909712 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		OTOG_HUMAN (48-397): 3.72e-12: 71: 13.21
+	Hs
		647025 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		OTOG_HUMAN (48-397): 3.72e-12: 71: 13.21
+	Hs
		683472 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		OTOG_HUMAN (48-397): 3.72e-12: 71: 13.21