HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: HDAC9 (Q9UKV0)
Histone deacetylase 9 (HD9) (EC 3.5.1.98) (Histone deacetylase 7B) (HD7) (HD7b) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR)
Gene: HDAC9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	20936779
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0140297 - DNA-binding transcription factor binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1011
+	Hs
		910144 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		HDAC9_HUMAN (1-1011): 0: 799: 100.00
+	Hs
		880673 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		HDAC4_HUMAN (1-1009): 0: 691: 54.67
+	Hs
		880661 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		HDAC4_HUMAN (1-1009): 0: 691: 54.67
+	Hs
		646756 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		HDAC4_HUMAN (1-1009): 0: 691: 54.67
+	Hs
		927670 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		HDAC5_HUMAN (1-1008): 0: 612: 55.67
+	Hs
		910173 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		HDAC5_HUMAN (1-1008): 0: 612: 55.67
+	Mm
		910239 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		Q3UJF1_MOUSE (1-1008): 0: 609: 54.42
+	Mm
		910352 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		HDAC5_MOUSE (1-1008): 0: 606: 53.75
+	Hs
		927340 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		HDAC7_HUMAN (75-1008): 1.75e-170: 525: 41.57
+	Hs
		909856 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		HDAC7_HUMAN (75-1008): 1.75e-170: 525: 41.57
+	Hs
		647138 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		HDAC7_HUMAN (75-1008): 1.75e-170: 525: 41.57
+	Dm
		664611 1433Z_DROME (1-245): 3.35e-143: 402: 81.22		Q59E49_DROME (21-1009): 1.26e-153: 488: 28.83
+	Mm
		910299 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		HDAC7_MOUSE (71-1008): 2.68e-155: 485: 41.45
+	Hs
		909530 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		HDAC1_HUMAN (623-1009): 3.2e-140: 430: 23.49
+	Hs
		927372 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		HDAC2_HUMAN (622-1009): 4.74e-130: 404: 22.67
+	Hs
		177251 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		HDAC3_HUMAN (631-1007): 9.3e-131: 404: 22.34
+	Hs
		177204 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		HDAC3_HUMAN (631-1007): 9.3e-131: 404: 22.34
+	Hs
		927619 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		HDAC6_HUMAN (564-1009): 2e-107: 363: 30.95
+	Hs
		910121 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		HDAC6_HUMAN (564-1009): 2e-107: 363: 30.95
+	Dm
		664668 1433Z_DROME (1-245): 3.35e-143: 402: 81.22		Q9VYF3_DROME (21-445): 3.14e-20: 99.3: 21.51