Protein: DAB2
Disabled homolog 2 (Adaptor molecule disabled-2) (Differentially expressed in ovarian carcinoma 2) (DOC-2) (Differentially-expressed protein 2)

Gene: DAB2
Organism: Homo sapiens
Interactions: 135
UniProt ID: P98082

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001650 - fibrillar center
GO:0005737 - cytoplasm
GO:0005765 - lysosomal membrane
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

421923

A4
Amyloid-beta precursor protein

2

20

Small-scale

0.789

High

1022203

MYO6
Unconventional myosin-VI

12

4

Small-scale

0.761

High

1022188

DVL3
Segment polarity protein dishevelled homolog DVL-3

1

20

Small-scale

0.747

High

159608

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

16

Small-scale

0.724

High

1022154

FCHO2
F-BAR domain only protein 2

4

8

Small-scale

0.705

High

987543

GRB2
Growth factor receptor-bound protein 2

4

20

Small-scale

0.688

High

1022189

SH3K1
SH3 domain-containing kinase-binding protein 1

3

20

Small-scale

0.658

High

159336

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

20

Small-scale

0.647

High

907306

APLP1
Amyloid beta precursor like protein 1

1

15

Small-scale

0.647

High

1022151

APLP2
Amyloid beta precursor like protein 2

1

16

Small-scale

0.647

High

483324

CLCB
Clathrin light chain B

2

10

High-throughput

0.611

High

1022148

CLH1
Clathrin heavy chain 1

2

5

Small-scale

0.611

High

563624

CFTR
Cystic fibrosis transmembrane conductance regulator

2

0

Small-scale

0.585

High

323702

AP2A2
AP-2 complex subunit alpha-2

2

20

Small-scale

0.584

High

483071

CLCA
Clathrin light chain A

2

10

Small-scale

0.584

High

988948

AP2B1
AP-2 complex subunit beta

2

20

Small-scale

0.584

High

443304

CDK1
Cyclin-dependent kinase 1

1

4

Small-scale

0.578

High

1014472

SMAD3
Mothers against decapentaplegic homolog 3

1

3

Small-scale

0.578

High

1022167

SMAD2
Mothers against decapentaplegic homolog 2

1

3

Small-scale

0.578

High

1022147

LRP2
Low-density lipoprotein receptor-related protein 2

1

20

Small-scale

0.573

High

557227

SRC
Proto-oncogene tyrosine-protein kinase Src

1

20

Small-scale

0.561

High

834172

CSK
Tyrosine-protein kinase CSK

1

20

Small-scale

0.561

High

1022158

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

1

Small-scale

0.561

High

1022172

DAB2P
Disabled homolog 2-interacting protein

1

16

Small-scale

0.561

High

171692

GAK
Cyclin-G-associated kinase

1

10

High-throughput

0.536

High

389288

FINC
Fibronectin

1

3

High-throughput

0.536

High

395911

ESR1
Estrogen receptor

1

16

High-throughput

0.536

High

637457

FLNA
Filamin-A

1

2

High-throughput

0.536

High

787381

TGFR1
TGF-beta receptor type-1

1

1

Small-scale

0.536

High

788897

TGFR2
TGF-beta receptor type-2

1

1

Small-scale

0.536

High

862802

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

16

High-throughput

0.536

High

866644

CAZA2
F-actin-capping protein subunit alpha-2

1

2

High-throughput

0.536

High

958244

ARP2
Actin-related protein 2

1

5

High-throughput

0.536

High

968256

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

3

High-throughput

0.536

High

1022157

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

2

High-throughput

0.536

High

1022166

MARE1
Microtubule-associated protein RP/EB family member 1

1

2

High-throughput

0.536

High

1022170

DREB
Drebrin

1

5

High-throughput

0.536

High

1022171

DCAF6
DDB1- and CUL4-associated factor 6

1

10

High-throughput

0.536

High

1022179

SYNPO
Synaptopodin

1

5

High-throughput

0.536

High

1022186

MY18A
Unconventional myosin-XVIIIa

1

1

High-throughput

0.536

High

1022191

REPS1
RalBP1-associated Eps domain-containing protein 1

1

20

High-throughput

0.536

High

1022192

MYO19
Unconventional myosin-XIX

1

5

High-throughput

0.536

High

1022198

ANLN
Anillin

1

3

High-throughput

0.536

High

1022199

BMP2K
BMP-2-inducible protein kinase

1

6

High-throughput

0.536

High

1022200

GTSE1
G2 and S phase-expressed protein 1

1

3

High-throughput

0.536

High

1022202

LIMA1
LIM domain and actin-binding protein 1

1

4

High-throughput

0.536

High

1022205

AKT3
RAC-gamma serine/threonine-protein kinase

1

6

High-throughput

0.536

High

287552

LRP6
Low-density lipoprotein receptor-related protein 6

1

20

Small-scale

0.515

High

772744

MYH9
Myosin-9

1

0

High-throughput

0.513

High

874773

SPB4
Serpin B4

1

0

High-throughput

0.513

High

1022177

HDGR2
Hepatoma-derived growth factor-related protein 2

1

0

High-throughput

0.513

High

1022196

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

3

High-throughput

0.508

High

155657

FCHO1
F-BAR domain only protein 1

1

7

Small-scale

0.501

High

181089

AXIN1
Axin-1

1

3

Small-scale

0.501

High

376496

LDLR
Low-density lipoprotein receptor

1

20

Small-scale

0.501

High

424654

KPCG
Protein kinase C gamma type

1

12

Small-scale

0.501

High

436654

KPCB
Protein kinase C beta type

1

12

Small-scale

0.501

High

486685

FGR
Tyrosine-protein kinase Fgr

1

20

Small-scale

0.501

High

1022150

KPCD
Protein kinase C delta type

1

12

Small-scale

0.501

High

1022153

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

20

Small-scale

0.501

High

1022159

LRP8
Low-density lipoprotein receptor-related protein 8

1

20

Small-scale

0.501

High

1022187

SHIP1
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1

1

3

Small-scale

0.501

High

1022193

SGIP1
SH3-containing GRB2-like protein 3-interacting protein 1

1

6

Small-scale

0.501

High

361220

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.493

High

505543

ATX1L
Ataxin-1-like

1

2

High-throughput

0.481

High

1022155

CDC16
Cell division cycle protein 16 homolog

1

2

High-throughput

0.481

High

1022168

ITSN1
Intersectin-1

1

20

High-throughput

0.481

High

964219

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.480

High

126546

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

170084

AURKA
Aurora kinase A

1

3

Small-scale

0.479

High

172700

XPO1
Exportin-1

1

5

High-throughput

0.479

High

189512

STX7
Syntaxin-7

1

5

High-throughput

0.479

High

218060

TGON2
Trans-Golgi network integral membrane protein 2

1

7

High-throughput

0.479

High

225993

STX6
Syntaxin-6

1

5

High-throughput

0.479

High

299536

TRIO
Triple functional domain protein

1

2

Small-scale

0.479

High

338455

SC24B
Protein transport protein Sec24B

1

1

Small-scale

0.479

High

344671

AP2A1
AP-2 complex subunit alpha-1

1

20

Small-scale

0.479

High

363131

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.479

High

425444

ISG15
Ubiquitin-like protein ISG15

1

6

High-throughput

0.479

High

440491

FYN
Tyrosine-protein kinase Fyn

1

20

High-throughput

0.479

High

462357

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

1

High-throughput

0.479

High

576356

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

2

Small-scale

0.479

High

580988

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

593965

NCK1
SH2/SH3 adapter protein NCK1

1

20

High-throughput

0.479

High

648480

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.479

High

699697

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

3

High-throughput

0.479

High

839742

EPS15
Epidermal growth factor receptor substrate 15

1

20

Small-scale

0.479

High

845599

MUC18
Cell surface glycoprotein MUC18

1

5

High-throughput

0.479

High

891114

GSK3A
Glycogen synthase kinase-3 alpha

1

6

High-throughput

0.479

High

891449

GSK3B
Glycogen synthase kinase-3 beta

1

6

High-throughput

0.479

High

952745

ACTB
Actin, cytoplasmic 1

1

5

Small-scale

0.479

High

961950

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

977934

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

986342

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

3

High-throughput

0.479

High

988274

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

1022152

PRDX1
Peroxiredoxin-1

1

1

Small-scale

0.479

High

1022160

BECN1
Beclin-1

1

1

Small-scale

0.479

High

1022161

TNIP1
TNFAIP3-interacting protein 1

1

8

High-throughput

0.479

High

1022162

KIF14
Kinesin-like protein KIF14

1

3

High-throughput

0.479

High

1022163

NONO
Non-POU domain-containing octamer-binding protein

1

1

Small-scale

0.479

High

1022164

SC23B
Protein transport protein Sec23B

1

1

Small-scale

0.479

High

1022165

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.479

High

1022169

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

6

Small-scale

0.479

High

1022173

LTOR1
Ragulator complex protein LAMTOR1

1

4

High-throughput

0.479

High

1022175

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

1022176

ATG9A
Autophagy-related protein 9A

1

3

High-throughput

0.479

High

1022178

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

3

High-throughput

0.479

High

1022181

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

2

Small-scale

0.479

High

1022183

SMAP2
Stromal membrane-associated protein 2

1

8

High-throughput

0.479

High

1022184

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

4

High-throughput

0.479

High

1022185

HS105
Heat shock protein 105 kDa

1

3

Small-scale

0.479

High

1022190

AP2M1
AP-2 complex subunit mu

1

7

Small-scale

0.479

High

1022194

ACE2
Angiotensin-converting enzyme 2

1

2

High-throughput

0.479

High

1022197

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

1022201

MALT1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1

1

9

Small-scale

0.479

High

251567

CCNT1
Cyclin-T1

1

0

Small-scale

0.458

High

291298

NU155
Nuclear pore complex protein Nup155

1

0

Small-scale

0.458

High

431550

AP2A
Transcription factor AP-2-alpha

1

0

Small-scale

0.458

High

659763

SAHH
Adenosylhomocysteinase

1

0

Small-scale

0.458

High

1022149

IFM3
Interferon-induced transmembrane protein 3

1

0

High-throughput

0.458

High

1022204

RTRAF
RNA transcription, translation and transport factor protein

1

0

Small-scale

0.458

High

765392

BMI1
Polycomb complex protein BMI-1

1

3

High-throughput

0.445

High

922566

AP2S1
AP-2 complex subunit sigma

1

11

High-throughput

0.445

High

1022174

PKHA7
Pleckstrin homology domain-containing family A member 7

1

9

High-throughput

0.445

High

1022195

ZDHC5
Palmitoyltransferase ZDHHC5

1

2

High-throughput

0.445

High

1022207

NGN3
Neurogenin-3

1

1

High-throughput

0.445

High

888595

YLPM1
YLP motif-containing protein 1

1

8

Small-scale

0.437

High

402904

ANXA1
Annexin A1

1

0

Small-scale

0.426

High

333747

FKBP9
Peptidyl-prolyl cis-trans isomerase FKBP9

1

1

High-throughput

0.407

High

1022180

S2541
Mitochondrial carrier protein SCaMC-3L

3

0

High-throughput

0.347

High

1022182

S43A3
Equilibrative nucleobase transporter 1

1

0

High-throughput

0.279

Low

733908

P5CR1
Pyrroline-5-carboxylate reductase 1, mitochondrial

1

0

Small-scale

0.249

Low

1022156

SF3B2
Splicing factor 3B subunit 2

1

0

Small-scale

0.249

Low

1022206

ACOT9
Acyl-coenzyme A thioesterase 9, mitochondrial

1

0

Small-scale

0.249

Low

552940

PIP
Prolactin-inducible protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025