HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: NISCH (Q9Y2I1)
Nischarin (Imidazoline receptor 1) (I-1) (IR1) (Imidazoline receptor antisera-selected protein) (hIRAS) (Imidazoline-1 receptor) (I1R) (Imidazoline-1 receptor candidate protein) (I-1 receptor candidate protein) (I1R candidate protein)
Gene: NISCH

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 1504
+	Hs
		910183 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		NISCH_HUMAN (1-1504): 0: 1812: 100.00
+	At
		788442 14331_ARATH (3-238): 4.25e-142: 400: 64.58		EMS1_ARATH (1-343): 1.84e-56: 217: 14.01
+	At
		788640 14333_ARATH (3-239): 1.48e-141: 398: 64.73		EMS1_ARATH (1-343): 1.84e-56: 217: 14.01
+	Hs
		927479 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		LGR4_HUMAN (100-537): 1.25e-40: 165: 15.65
+	At
		186958 14332_ARATH (3-239): 6.89e-143: 401: 65.15		BRI1_ARATH (317-670): 1.64e-36: 153: 13.82
+	Hs
		904823 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		CEP97_HUMAN (221-554): 1.17e-54: 209: 25.85
+	At
		965375 14332_ARATH (3-239): 6.89e-143: 401: 65.15		BRL2_ARATH (6-275): 3.1e-24: 113: 11.22
+	At
		788683 14333_ARATH (3-239): 1.48e-141: 398: 64.73		BRL2_ARATH (6-275): 3.1e-24: 113: 11.22
+	Hs
		927034 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		SCRIB_HUMAN (209-577): 1.3e-17: 91.7: 18.01
+	Hs
		910166 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		SHOC2_HUMAN (209-418): 3.55e-16: 85.9: 23.21
+	At
		965369 14332_ARATH (3-239): 6.89e-143: 401: 65.15		CLV1_ARATH (3-154): 2.61e-16: 87: 6.63
+	Hs
		646881 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		SCRIB_HUMAN (209-577): 1.3e-17: 91.7: 18.01
+	Hs
		683339 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		SCRIB_HUMAN (209-577): 1.3e-17: 91.7: 18.01
+	Hs
		905066 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		LGR4_HUMAN (100-537): 1.25e-40: 165: 15.65
+	Hs
		683820 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		SHOC2_HUMAN (209-418): 3.55e-16: 85.9: 23.21
+	Hs
		982215 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		CNTRL_HUMAN (304-478): 2.54e-36: 153: 28.89
+	Hs
		904552 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		SCRIB_HUMAN (209-577): 1.3e-17: 91.7: 18.01
+	Hs
		982003 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		SCRIB_HUMAN (209-577): 1.3e-17: 91.7: 18.01
+	Hs
		684030 1433S_HUMAN (1-237): 8.27e-104: 302: 71.97		SCRIB_HUMAN (209-577): 1.3e-17: 91.7: 18.01