HitPredict

Interactor 1: 2ABA (P63151)
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PP2A subunit B isoform B55-alpha) (PP2A subunit B isoform PR55-alpha) (PP2A subunit B isoform R2-alpha) (PP2A subunit B isoform alpha)
Gene: PPP2R2A

Interactor 2: FOXC2 (Q99958)
Forkhead box protein C2 (Forkhead-related protein FKHL14) (Mesenchyme fork head protein 1) (MFH-1 protein) (Transcription factor FKH-14)
Gene: FOXC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 23878394
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 447 Hs			1 501
+	Hs
		1146371 2ABD_HUMAN (8-447): 0: 829: 88.86		FOXC2_HUMAN (1-501): 1.02e-87: 280: 100.00
+	Hs
		927803 2ABA_HUMAN (1-447): 0: 852: 100.00		FOXC1_HUMAN (1-501): 6.45e-58: 203: 36.56
+	Hs
		1021123 2ABD_HUMAN (8-447): 0: 829: 88.86		FOXC1_HUMAN (1-501): 6.45e-58: 203: 36.56
+	Hs
		208907 2ABA_HUMAN (1-447): 0: 852: 100.00		FOXS1_HUMAN (67-345): 5.9e-52: 180: 37.63
+	Hs
		927822 2ABA_HUMAN (1-447): 0: 852: 100.00		FX4L6_HUMAN (43-290): 9.93e-47: 169: 34.54
+	Hs
		927804 2ABA_HUMAN (1-447): 0: 852: 100.00		FOXD4_HUMAN (29-320): 9.17e-44: 162: 29.01
+	Hs
		208916 2ABD_HUMAN (8-447): 0: 829: 88.86		FOXS1_HUMAN (67-345): 5.9e-52: 180: 37.63
+	Hs
		1146383 2ABD_HUMAN (8-447): 0: 829: 88.86		FX4L1_HUMAN (43-306): 9.4e-48: 172: 32.51
+	Hs
		1110353 2ABD_HUMAN (8-447): 0: 829: 88.86		FX4L6_HUMAN (43-290): 9.93e-47: 169: 34.54
+	Hs
		1021194 2ABD_HUMAN (8-447): 0: 829: 88.86		FOXD4_HUMAN (29-320): 9.17e-44: 162: 29.01
+	Hs
		1021075 2ABD_HUMAN (8-447): 0: 829: 88.86		FOXF2_HUMAN (68-400): 1.27e-37: 145: 25.43
+	Dm
		737575 2ABA_DROME (9-445): 0: 793: 79.63		FD3_DROME (25-209): 2.19e-49: 177: 41.62
+	Hs
		236575 2ABB_HUMAN (26-447): 0: 798: 89.10		FOXD2_HUMAN (68-160): 8.42e-46: 168: 67.74
+	Hs
		1146394 2ABD_HUMAN (8-447): 0: 829: 88.86		FOXD3_HUMAN (64-160): 1.05e-31: 129: 69.39
+	Hs
		958788 2ABB_HUMAN (26-447): 0: 798: 89.10		FOXD3_HUMAN (64-160): 1.05e-31: 129: 69.39