Protein: ACTN2
Alpha-actinin-2 (Alpha-actinin skeletal muscle isoform 2) (F-actin cross-linking protein)

Gene: ACTN2
Organism: Mus musculus
Interactions: 21
UniProt ID: Q9JI91

Gene Ontology (top 5):
GO:0003713 - transcription coactivator activity
GO:0005509 - calcium ion binding
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0005865 - striated muscle thin filament
GO:0005925 - focal adhesion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1440839

LDB3
LIM domain-binding protein 3

2

16

Small-scale

0.819

High

548973

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

6

Small-scale

0.648

High

1247217

NEB2
Neurabin-2

3

20

Small-scale

0.646

High

977883

ACTA
Actin, aortic smooth muscle

1

13

High-throughput

0.618

High

1440837

ACTN2
Alpha-actinin-2

1

14

High-throughput

0.618

High

1440838

MYOZ2
Myozenin-2

1

7

High-throughput

0.618

High

1029245

NMDE2
Glutamate receptor ionotropic, NMDA 2B

2

9

Small-scale

0.594

High

1257706

TRPV1
Transient receptor potential cation channel subfamily V member 1

1

12

High-throughput

0.553

High

771506

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

9

High-throughput

0.536

High

591085

KPCE
Protein kinase C epsilon type

1

3

Small-scale

0.514

High

205139

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

1

High-throughput

0.479

High

1365316

GRIP1
Glutamate receptor-interacting protein 1

1

19

Small-scale

0.479

High

554298

RAPSN
43 kDa receptor-associated protein of the synapse

1

0

Small-scale

0.458

High

1440840

SRCN1
SRC kinase signaling inhibitor 1

1

5

High-throughput

0.445

High

1423827

RAVR1
Ribonucleoprotein PTB-binding 1

1

1

Small-scale

0.439

High

618523

ANDR
Androgen receptor

1

11

Small-scale

0.437

High

928081

ATX1
Ataxin-1

1

1

High-throughput

0.437

High

1296384

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

14

High-throughput

0.437

High

1317417

ALMS1
Centrosome-associated protein ALMS1

1

8

Small-scale

0.417

High

960645

RAB6B
Ras-related protein Rab-6B

1

7

High-throughput

0.407

High


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Last updated: 11Aug2025