HitPredict

Interactor 1: 2ABA (P63151)
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PP2A subunit B isoform B55-alpha) (PP2A subunit B isoform PR55-alpha) (PP2A subunit B isoform R2-alpha) (PP2A subunit B isoform alpha)
Gene: PPP2R2A

Interactor 2: SIK2 (Q9H0K1)
Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)
Gene: SIK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.50	0.578

Property	Details
Experiments	33947818, 36736316, 16306228
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 447 Hs			1 926
+	Hs
		958766 2ABB_HUMAN (26-447): 0: 798: 89.10		SIK2_HUMAN (1-926): 0: 744: 100.00
+	Hs
		1327883 2ABG_HUMAN (25-447): 0: 783: 84.63		SIK2_HUMAN (1-926): 0: 744: 100.00
+	Hs
		647870 2ABA_HUMAN (1-447): 0: 852: 100.00		MARK3_HUMAN (8-677): 2.57e-152: 469: 30.77
+	Hs
		647873 2ABB_HUMAN (26-447): 0: 798: 89.10		MARK3_HUMAN (8-677): 2.57e-152: 469: 30.77
+	Hs
		958714 2ABB_HUMAN (26-447): 0: 798: 89.10		MARK2_HUMAN (1-673): 4.94e-146: 454: 31.29