Interactor 1: HMGB1 (P63158)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: TLR2 (Q9QUN7)
Toll-like receptor 2 (CD antigen CD282)
Gene: TLR2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 16267105
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0006954 - inflammatory response
GO:0032728 - positive regulation of interferon-beta production
GO:0032731 - positive regulation of interleukin-1 beta production
GO:0032755 - positive regulation of interleukin-6 production
and 5 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 215
Mm

1 784
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024