HitPredict

Interactor 1: SUMO1 (P63165)
Small ubiquitin-related modifier 1 (SUMO-1) (GAP-modifying protein 1) (GMP1) (SMT3 homolog 3) (Sentrin) (Ubiquitin-homology domain protein PIC1) (Ubiquitin-like protein SMT3C) (Smt3C) (Ubiquitin-like protein UBL1)
Gene: SUMO1

Interactor 2: EPAS1 (Q99814)
Endothelial PAS domain-containing protein 1 (EPAS-1) (Basic-helix-loop-helix-PAS protein MOP2) (Class E basic helix-loop-helix protein 73) (bHLHe73) (HIF-1-alpha-like factor) (HLF) (Hypoxia-inducible factor 2-alpha) (HIF-2-alpha) (HIF2-alpha) (Member of PAS protein 2) (PAS domain-containing protein 2)
Gene: EPAS1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20661221
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016607 - nuclear speck
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 101 Hs			1 870
+	Hs
		928107 SUMO1_HUMAN (1-101): 1.01e-41: 134: 100.00		HIF1A_HUMAN (3-868): 0: 553: 42.32
+	Mm
		928248 SUMO1_MOUSE (1-101): 1.01e-41: 134: 100.00		HIF1A_MOUSE (3-787): 0: 549: 43.60
+	Hs
		879116 SUMO3_HUMAN (1-97): 1.65e-37: 123: 47.42		HIF1A_HUMAN (3-868): 0: 553: 42.32