Protein: MYH6
Myosin-6 (Myosin heavy chain 6) (Myosin heavy chain, cardiac muscle alpha isoform) (MyHC-alpha)

Gene: MYH6
Organism: Mus musculus
Interactions: 40
UniProt ID: Q02566

Gene Ontology (top 5):
GO:0000146 - microfilament motor activity
GO:0001701 - in utero embryonic development
GO:0001725 - stress fiber
GO:0002026 - regulation of the force of heart contraction
GO:0002027 - regulation of heart rate

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

59762

MYH7B
Myosin-7B

1

17

High-throughput

0.618

High

563088

MYH8
Myosin-8

1

17

High-throughput

0.618

High

906631

MLRV
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform

1

19

High-throughput

0.618

High

945615

ACTN4
Alpha-actinin-4

1

10

High-throughput

0.618

High

977876

ACTA
Actin, aortic smooth muscle

1

13

High-throughput

0.618

High

1037830

MYH6
Myosin-6

1

16

High-throughput

0.618

High

1037835

MYH1
Myosin-1

1

17

High-throughput

0.618

High

1037844

DYST
Dystonin

1

12

High-throughput

0.618

High

267098

MYPC3
Myosin-binding protein C, cardiac-type

2

10

Small-scale

0.591

High

421223

ALDOA
Fructose-bisphosphate aldolase A

1

2

High-throughput

0.479

High

456041

KCRM
Creatine kinase M-type

1

1

High-throughput

0.479

High

483499

MYL3
Myosin light chain 3

1

16

High-throughput

0.479

High

968848

PRS4
26S proteasome regulatory subunit 4

1

1

High-throughput

0.479

High

1037831

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

3

High-throughput

0.479

High

1037833

Q3UIK0
Myosin-binding protein C, cardiac-type

1

9

High-throughput

0.479

High

1037836

MYOM1
Myomesin-1

1

8

High-throughput

0.479

High

1037837

VINC
Vinculin

1

2

High-throughput

0.479

High

1037843

DYH5
Dynein axonemal heavy chain 5

1

2

High-throughput

0.479

High

1037845

FBX32
F-box only protein 32

1

7

High-throughput

0.479

High

204363

ATIF1
ATPase inhibitor, mitochondrial

1

0

High-throughput

0.458

High

569626

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

0

High-throughput

0.458

High

898048

TNNT2
Troponin T, cardiac muscle

1

0

High-throughput

0.458

High

1037832

SYRM
Probable arginine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

1037841

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

0

High-throughput

0.458

High

591040

KPCE
Protein kinase C epsilon type

1

3

Small-scale

0.445

High

98201

ZC3HD
Zinc finger CCCH domain-containing protein 13

1

14

High-throughput

0.437

High

108652

G3X9H5
Huntingtin

1

2

High-throughput

0.437

High

469597

MDHM
Malate dehydrogenase, mitochondrial

1

3

High-throughput

0.437

High

638869

ENOB
Beta-enolase

1

4

High-throughput

0.437

High

1023451

ARVC
Splicing regulator ARVCF

1

6

High-throughput

0.437

High

1037838

FACD2
Fanconi anemia group D2 protein homolog

1

6

High-throughput

0.437

High

1037839

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

4

High-throughput

0.437

High

1037840

Q8BUJ0
Titin

1

9

High-throughput

0.437

High

1037846

CCD89
Coiled-coil domain-containing protein 89

1

1

High-throughput

0.437

High

1037847

SON
Protein SON

1

1

High-throughput

0.437

High

968079

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

8

High-throughput

0.407

High

465923

CO4A2

1

0

High-throughput

0.249

Low

1037834

RBM27
RNA-binding protein 27

1

0

High-throughput

0.249

Low

1037842

DJC28
DnaJ homolog subfamily C member 28

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025