HitPredict

Interactor 1: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Interactor 2: PAK1 (Q13153)
Serine/threonine-protein kinase PAK 1 (EC 2.7.11.1) (Alpha-PAK) (p21-activated kinase 1) (PAK-1) (p65-PAK)
Gene: PAK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 0.60 0.702

The method score is based on:

Property Details
Experiments 15193260, 21988832, 17389360, 32814053
Identification Methods two hybrid, pull down, affinity chromatography technology, enzymatic study, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006915 - apoptotic process
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 89
Hs

1 545
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024