HitPredict

Interactor 1: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Interactor 2: AMRA1 (Q9C0C7)
Activating molecule in BECN1-regulated autophagy protein 1 (DDB1- and CUL4-associated factor 3)
Gene: AMBRA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.702

Property	Details
Experiments	20921139, 30166453, 27173435, 35271311
Identification Methods	two hybrid, affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0005856 - cytoskeleton
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 89 Hs			1 1298
+	Hs
		1291289 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		AMRA1_HUMAN (1-1298): 0: 1603: 100.00
+	Mm
		57123 DYL1_MOUSE (1-89): 1.96e-46: 145: 100.00		AMRA1_MOUSE (1-1298): 0: 1529: 95.69
+	Hs
		792964 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		LIS1_HUMAN (123-346): 3.66e-35: 141: 11.45
+	Hs
		793023 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		LIS1_HUMAN (123-346): 3.66e-35: 141: 11.45