HitPredict

Interactor 1: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Interactor 2: TRAK1 (Q9UPV9)
Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase-interacting protein) (Protein Milton)
Gene: TRAK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol GO:1904115 - axon cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 89 Hs			1 953
+	Hs
		1291333 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		TRAK1_HUMAN (1-953): 0: 646: 100.00
+	Hs
		551662 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		DESP_HUMAN (38-579): 1.38e-20: 100: 10.28
+	Hs
		928339 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		MRCKG_HUMAN (23-365): 5.69e-20: 98.5: 15.43
+	Hs
		1150626 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		MRCKG_HUMAN (23-365): 5.69e-20: 98.5: 15.43
+	Hs
		148656 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		CTRO_HUMAN (33-527): 4.9e-19: 95.4: 11.83
+	Hs
		928542 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		MYO5A_HUMAN (47-567): 2.47e-18: 93.1: 11.22
+	Dm
		115259 DYL1_DROME (1-89): 1.36e-46: 145: 94.38		M9PEK6_DROME (20-603): 4.54e-18: 92.4: 11.64
+	Hs
		1291342 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		MYO5A_HUMAN (47-567): 2.47e-18: 93.1: 11.22