HitPredict

Interactor 1: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Interactor 2: MTCL1 (Q9Y4B5)
Microtubule cross-linking factor 1 (Coiled-coil domain-containing protein 165) (PAR-1-interacting protein) (SOGA family member 2)
Gene: MTCL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26496610, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0005737 - cytoplasm GO:0005856 - cytoskeleton
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 89 Hs			1 1905
+	Hs
		1291340 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		MTCL1_HUMAN (1-1905): 0: 827: 100.00
+	Hs
		301279 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		MTCL2_HUMAN (52-1172): 3.52e-13: 77.4: 10.52
+	Hs
		301312 DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26		MTCL2_HUMAN (52-1172): 3.52e-13: 77.4: 10.52
+	Hs
		551662 DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00		DESP_HUMAN (294-843): 6.21e-12: 73.4: 16.70