HitPredict

Interactor 1: DYLT1 (P63172)
Dynein light chain Tctex-type 1 (Protein CW-1) (T-complex testis-specific protein 1 homolog)
Gene: DYNLT1

Interactor 2: DC2I1 (Q8WVS4)
Cytoplasmic dynein 2 intermediate chain 1 (Dynein 2 intermediate chain 1) (WD repeat-containing protein 60)
Gene: DYNC2I1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	27173435, 26638075, 28718761
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005868 - cytoplasmic dynein complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 113 Hs			1 1066
+	Hs
		1261757 DYT2B_HUMAN (2-110): 2.72e-36: 122: 29.09		DC2I1_HUMAN (1-1066): 0: 812: 100.00
+	Hs
		1127235 DYLT4_HUMAN (2-111): 9.76e-27: 100: 19.47		DC2I1_HUMAN (1-1066): 0: 812: 100.00
+	Hs
		148060 DYLT1_HUMAN (1-113): 1.19e-51: 160: 100.00		DC1I1_HUMAN (376-1056): 5.44e-177: 533: 16.90
+	Hs
		148055 DYLT3_HUMAN (1-113): 1.14e-46: 147: 54.39		DC1I1_HUMAN (376-1056): 5.44e-177: 533: 16.90
+	Hs
		928590 DYLT1_HUMAN (1-113): 1.19e-51: 160: 100.00		DC1I2_HUMAN (382-1056): 3.33e-166: 505: 16.71
+	Hs
		850528 DYLT3_HUMAN (1-113): 1.14e-46: 147: 54.39		DC1I2_HUMAN (382-1056): 3.33e-166: 505: 16.71
+	Dm
		1096837 DYLT_DROME (5-113): 9.87e-45: 142: 70.64		DYIN_DROME (566-1056): 3.64e-112: 364: 19.68
+	Dm
		54881 DYLT_DROME (5-113): 9.87e-45: 142: 70.64		A1ZA72_DROME (2-292): 5.21e-09: 63.1: 9.33