Interactor 1: SKP1 (P63208)
S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (p19A) (Organ of Corti protein 2) (OCP-2) (Organ of Corti protein II) (OCP-II) (RNA polymerase II elongation factor-like protein) (SIII) (Transcription elongation factor B polypeptide 1-like) (p19skp1)
Gene: SKP1
Interactor 2: FBX4 (Q9UKT5)
F-box only protein 4
Gene: FBXO4
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.986 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27705803, 32296183, 10531035, 33961781, 20181953, 26087183, 28514442, 29142209, 17353931, 31210753, 31130363, 16278047, 24019069, unassigned1304, 21242966 |
| Identification Methods | affinity chromatography technology, two hybrid, pull down, x-ray crystallography, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, anti bait coimmunoprecipitation, validated two hybrid, mammalian protein protein interaction trap and 1 others
more... |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | F-box-like~Skp1 |
| Common GO terms | GO:0000209 - protein polyubiquitination GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016567 - protein ubiquitination GO:0019005 - SCF ubiquitin ligase complex and 2 others more... |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
