HitPredict

Interactor 1: PRRT2 (E9PUL5)
Proline-rich transmembrane protein 2 (Dispanin subfamily B member 3) (DSPB3)
Gene: PRRT2

Interactor 2: RAC3 (P60764)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36808153
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0043005 - neuron projection GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 346 Mm			1 192
+	Mm
		92923 PRRT2_MOUSE (1-346): 2.71e-58: 193: 100.00		CDC42_MOUSE (1-192): 3.66e-77: 230: 68.75
+	Hs
		925434 MINK1_HUMAN (53-258): 1.75e-22: 100: 21.64		RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71
+	Hs
		545493 MINK1_HUMAN (53-258): 1.75e-22: 100: 21.64		RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54
+	Hs
		1233542 MINK1_HUMAN (53-258): 1.75e-22: 100: 21.64		RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32
+	Hs
		892483 MINK1_HUMAN (53-258): 1.75e-22: 100: 21.64		RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00
+	Hs
		564611 MINK1_HUMAN (53-258): 1.75e-22: 100: 21.64		RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49
+	Ce
		136793 UNC89_CAEEL (8-236): 3.5e-14: 75.8: 13.08		RAC1_CAEEL (1-192): 1.53e-82: 244: 81.25
+	Hs
		297823 K0754_HUMAN (9-293): 4.88e-12: 69.3: 11.85		RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71
+	Hs
		925387 MICA3_HUMAN (21-203): 5e-11: 66.2: 16.15		RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71
+	Hs
		297812 K0754_HUMAN (9-293): 4.88e-12: 69.3: 11.85		RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54
+	Hs
		297840 K0754_HUMAN (9-293): 4.88e-12: 69.3: 11.85		RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32
+	Ce
		104464 UNC89_CAEEL (8-236): 3.5e-14: 75.8: 13.08		G5EBV3_CAEEL (2-192): 2.34e-77: 231: 63.87
+	Hs
		1186089 MICA3_HUMAN (21-203): 5e-11: 66.2: 16.15		RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32
+	Hs
		297819 K0754_HUMAN (9-293): 4.88e-12: 69.3: 11.85		RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00
+	Hs
		297827 K0754_HUMAN (9-293): 4.88e-12: 69.3: 11.85		RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79
+	Hs
		892450 MICA3_HUMAN (21-203): 5e-11: 66.2: 16.15		RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00
+	Ce
		136794 UNC89_CAEEL (8-236): 3.5e-14: 75.8: 13.08		CDC42_CAEEL (1-192): 3.66e-75: 225: 67.71
+	Hs
		297820 K0754_HUMAN (9-293): 4.88e-12: 69.3: 11.85		RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32
+	Hs
		297809 K0754_HUMAN (9-293): 4.88e-12: 69.3: 11.85		RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79
+	Hs
		564587 MICA3_HUMAN (21-203): 5e-11: 66.2: 16.15		RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49