Interactor 1: NEC1 (P63239)
Neuroendocrine convertase 1 (NEC 1) (EC 3.4.21.93) (Furin homolog) (PC3) (Prohormone convertase 1) (Propeptide-processing protease) (Proprotein convertase 1) (PC1)
Gene: Pcsk1

Interactor 2: NEC1 (P63239)
Neuroendocrine convertase 1 (NEC 1) (EC 3.4.21.93) (Furin homolog) (PC3) (Prohormone convertase 1) (Propeptide-processing protease) (Proprotein convertase 1) (PC1)
Gene: Pcsk1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 19376969
Identification Methods nuclear magnetic resonance, cosedimentation in solution
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains P_proprotein~Peptidase_S8, Peptidase_S8~Peptidase_S8
Common GO terms GO:0004175 - endopeptidase activity
GO:0004252 - serine-type endopeptidase activity
GO:0005615 - extracellular space
GO:0005788 - endoplasmic reticulum lumen
GO:0005802 - trans-Golgi network
and 30 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 753
Mm

1 753
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Dm
+ Tk
+ Bs
+ At
+ Zm
+ Pf
+ Hs

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Last updated: 15 Jul 2024