HitPredict

Interactor 1: RACK1 (P63244)
Small ribosomal subunit protein RACK1 (Cell proliferation-inducing gene 21 protein) (Guanine nucleotide-binding protein subunit beta-2-like 1) (Guanine nucleotide-binding protein subunit beta-like protein 12.3) (Human lung cancer oncogene 7 protein) (HLC-7) (Receptor for activated C kinase) (Receptor of activated protein C kinase 1) [Cleaved into: Small ribosomal subunit protein RACK1, N-terminally processed (Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed) (Receptor of activated protein C kinase 1, N-terminally processed)]
Gene: RACK1

Interactor 2: WDR83 (Q9BRX9)
WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1)
Gene: WDR83

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.80	0.587

Property	Details
Experiments	22365833
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 315
+	Hs
		792967 RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00		LIS1_HUMAN (63-312): 8.99e-76: 239: 19.78
+	Hs
		929603 RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	Hs
		929610 RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00		SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47
+	Hs
		929579 RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00		POC1B_HUMAN (2-181): 1.28e-52: 181: 21.43
+	Hs
		903109 RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00		WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60
+	Hs
		209416 WDR5_HUMAN (3-219): 3.42e-62: 202: 26.70		PLRG1_HUMAN (2-312): 1.61e-88: 275: 23.15
+	Hs
		929692 RACK1_HUMAN (1-317): 2.18e-109: 322: 100.00		NLE1_HUMAN (184-315): 2.98e-35: 134: 22.54
+	Dm
		1358845 WDS_DROME (3-223): 1.09e-62: 204: 25.78		WDS_DROME (2-266): 8.48e-80: 248: 22.99
+	Hs
		792949 WDR5_HUMAN (3-219): 3.42e-62: 202: 26.70		LIS1_HUMAN (63-312): 8.99e-76: 239: 19.78
+	Dm
		1358859 WDS_DROME (3-223): 1.09e-62: 204: 25.78		FBXW7_DROME (2-258): 1.53e-61: 213: 21.81
+	Hs
		792935 LIS1_HUMAN (144-316): 6.1e-46: 162: 23.43		LIS1_HUMAN (63-312): 8.99e-76: 239: 19.78
+	Hs
		903418 WDR5_HUMAN (3-219): 3.42e-62: 202: 26.70		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	Mm
		925836 LIS1_MOUSE (144-316): 4.89e-46: 162: 23.43		LIS1_MOUSE (63-312): 6.3e-76: 239: 19.78
+	Hs
		903428 WDR5_HUMAN (3-219): 3.42e-62: 202: 26.70		SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47
+	Hs
		903077 WDR5_HUMAN (3-219): 3.42e-62: 202: 26.70		WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60
+	Hs
		903349 WDR5_HUMAN (3-219): 3.42e-62: 202: 26.70		WDR5B_HUMAN (138-312): 8.72e-50: 170: 22.22
+	Hs
		1240442 POC1A_HUMAN (2-177): 3.39e-46: 162: 23.86		POC1B_HUMAN (2-181): 1.28e-52: 181: 21.43
+	Hs
		903551 WDR5_HUMAN (3-219): 3.42e-62: 202: 26.70		NLE1_HUMAN (184-315): 2.98e-35: 134: 22.54
+	Sc
		630844 NLE1_YEAST (59-316): 3.4e-70: 228: 20.92		NLE1_YEAST (2-94): 1.96e-23: 101: 30.11