HitPredict

Interactor 1: ACTG (P63260)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: Actg1

Interactor 2: SMCA2 (Q6DIC0)
Probable global transcription activator SNF2L2 (EC 3.6.4.-) (ATP-dependent helicase SMARCA2) (BRG1-associated factor 190B) (BAF190B) (Protein brahma homolog) (SNF2-alpha) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2)
Gene: Smarca2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	19279220
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~HSA, Actin~SNF2-rel_dom
Common GO terms	GO:0005524 - ATP binding GO:0016787 - hydrolase activity
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 375 Mm			1 1577
+	Hs
		846794 ACTBL_HUMAN (2-375): 0: 734: 91.44		SMCA2_HUMAN (1-1577): 0: 1051: 93.82
+	Hs
		846742 ACTC_HUMAN (2-375): 0: 595: 94.39		SMCA2_HUMAN (1-1577): 0: 1051: 93.82
+	Mm
		929785 ACTG_MOUSE (1-375): 0: 604: 100.00		SMCA4_MOUSE (1-1575): 0: 999: 73.58
+	Hs
		846910 ACTB_HUMAN (1-375): 0: 604: 98.93		SMCA4_HUMAN (1-1575): 0: 985: 72.61
+	Hs
		846917 ACTG_HUMAN (1-375): 0: 604: 100.00		SMCA4_HUMAN (1-1575): 0: 985: 72.61
+	Hs
		846918 ACTC_HUMAN (2-375): 0: 595: 94.39		SMCA4_HUMAN (1-1575): 0: 985: 72.61
+	Hs
		846919 ACTS_HUMAN (2-375): 0: 594: 93.85		SMCA4_HUMAN (1-1575): 0: 985: 72.61
+	Xl
		292752 ACTB_XENLA (1-375): 0: 604: 98.93		Q4VQ79_XENLA (65-1577): 0: 963: 73.12
+	Dm
		501486 ACT1_DROME (2-375): 0: 600: 98.13		BRM_DROME (68-1566): 0: 854: 49.59
+	Dm
		361138 ACT2_DROME (2-375): 0: 598: 97.59		BRM_DROME (68-1566): 0: 854: 49.59
+	Hs
		229358 ACTC_HUMAN (2-375): 0: 595: 94.39		SMCA5_HUMAN (589-1562): 0: 793: 26.67
+	Hs
		891769 ACTB_HUMAN (1-375): 0: 604: 98.93		CHD4_HUMAN (385-1537): 0: 738: 22.48
+	Zm
		13638 A0A1D6FW13_MAIZE (3-375): 0: 591: 89.28		A0A1D6MT91_MAIZE (581-1572): 0: 750: 27.31
+	Hs
		891731 ACTB_HUMAN (1-375): 0: 604: 98.93		CHD3_HUMAN (310-1577): 0: 736: 22.41
+	Hs
		929837 ACTG_HUMAN (1-375): 0: 604: 100.00		CHD3_HUMAN (310-1577): 0: 736: 22.41
+	Hs
		932158 ACTC_HUMAN (2-375): 0: 595: 94.39		CHD4_HUMAN (385-1537): 0: 738: 22.48
+	Hs
		932125 ACTC_HUMAN (2-375): 0: 595: 94.39		CHD3_HUMAN (310-1577): 0: 736: 22.41
+	Mm
		929800 ACTG_MOUSE (1-375): 0: 604: 100.00		EP400_MOUSE (1053-1420): 1.29e-45: 183: 22.66