HitPredict

Interactor 1: VATE (P54611)
V-type proton ATPase subunit E (V-ATPase subunit E) (V-ATPase 26 kDa subunit) (Vacuolar proton pump subunit E)
Gene: Vha26

Interactor 2: VATH (Q9V3J1)
V-type proton ATPase subunit H (V-ATPase subunit H) (Vacuolar proton pump subunit H) (Vacuolar proton pump subunit SFD)
Gene: VhaSFD

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.69	1.00	0.835

Property	Details
Experiments	14605208, 22036573, 38944040
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	V-ATPase_H_N~vATP-synt_E
Common GO terms	GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain GO:0033181 - plasma membrane proton-transporting V-type ATPase complex GO:0046961 - proton-transporting ATPase activity, rotational mechanism GO:1902600 - proton transmembrane transport
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 226 Dm			1 468
+	Hs
		784810 VATE1_HUMAN (1-226): 3.27e-100: 291: 63.27		VATH_HUMAN (12-462): 0: 602: 53.38
+	Hs
		1381838 VATE2_HUMAN (1-225): 7.17e-90: 265: 60.89		VATH_HUMAN (12-462): 0: 602: 53.38
+	Sc
		645834 VATE_YEAST (2-226): 4.01e-76: 230: 34.36		VATH_YEAST (14-444): 4.55e-82: 263: 23.82