Protein: NUAK1
NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5) (ARK5) (Omphalocele kinase 1)

Gene: NUAK1
Organism: Homo sapiens
Interactions: 89
UniProt ID: O60285

Gene Ontology (top 5):
GO:0001650 - fibrillar center
GO:0002039 - p53 binding
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

229917

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

6

High-throughput

0.802

High

161260

MYPT1
Protein phosphatase 1 regulatory subunit 12A

2

7

Small-scale

0.789

High

225111

MYPT2
Protein phosphatase 1 regulatory subunit 12B

2

7

Small-scale

0.789

High

229975

PP12C
Protein phosphatase 1 regulatory subunit 12C

2

7

Small-scale

0.789

High

229909

LATS1
Serine/threonine-protein kinase LATS1

1

17

Small-scale

0.747

High

229967

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

4

9

Small-scale

0.702

High

229984

FBW1B
F-box/WD repeat-containing protein 11

4

7

Small-scale

0.699

High

229987

FBW1A
F-box/WD repeat-containing protein 1A

4

7

Small-scale

0.699

High

229920

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

16

High-throughput

0.691

High

229922

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

15

High-throughput

0.691

High

229925

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

1

6

High-throughput

0.691

High

229931

KI67
Proliferation marker protein Ki-67

1

7

High-throughput

0.691

High

229944

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

5

High-throughput

0.691

High

229974

PDIP3
Polymerase delta-interacting protein 3

1

2

High-throughput

0.691

High

229976

TARA
TRIO and F-actin-binding protein

1

8

High-throughput

0.691

High

229982

RAI14
Ankycorbin

1

7

High-throughput

0.691

High

229926

AKT1
RAC-alpha serine/threonine-protein kinase

1

17

Small-scale

0.647

High

229985

SRRM2
Serine/arginine repetitive matrix protein 2

2

6

High-throughput

0.621

High

229958

MPRIP
Myosin phosphatase Rho-interacting protein

1

9

High-throughput

0.618

High

229924

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

10

High-throughput

0.618

High

229934

PLK1
Serine/threonine-protein kinase PLK1

1

16

Small-scale

0.618

High

229943

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

16

Small-scale

0.618

High

229980

INCE
Inner centromere protein

1

11

High-throughput

0.618

High

229937

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

2

11

Small-scale

0.611

High

229942

1433F
14-3-3 protein eta

2

20

High-throughput

0.611

High

229912

P53
Cellular tumor antigen p53

1

1

Small-scale

0.608

High

229915

FYN
Tyrosine-protein kinase Fyn

1

6

High-throughput

0.590

High

229933

RASF2
Ras association domain-containing protein 2

1

0

High-throughput

0.586

High

196918

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

1

3

High-throughput

0.536

High

229907

UBR5
E3 ubiquitin-protein ligase UBR5

1

13

High-throughput

0.536

High

229908

CPSF4
Cleavage and polyadenylation specificity factor subunit 4

1

1

High-throughput

0.536

High

229911

ESR1
Estrogen receptor

1

9

High-throughput

0.536

High

229923

MCM3
DNA replication licensing factor MCM3

1

7

High-throughput

0.536

High

229927

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.536

High

229928

KINH
Kinesin-1 heavy chain

1

4

High-throughput

0.536

High

229929

MCM7
DNA replication licensing factor MCM7

1

6

High-throughput

0.536

High

229932

MCM2
DNA replication licensing factor MCM2

1

7

High-throughput

0.536

High

229940

KIF23
Kinesin-like protein KIF23

1

4

High-throughput

0.536

High

229946

CKAP5
Cytoskeleton-associated protein 5

1

15

High-throughput

0.536

High

229947

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

6

High-throughput

0.536

High

229948

UBP2L
Ubiquitin-associated protein 2-like

1

2

High-throughput

0.536

High

229949

DOCK1
Dedicator of cytokinesis protein 1

1

13

High-throughput

0.536

High

229952

TSR1
Pre-rRNA-processing protein TSR1 homolog

1

1

High-throughput

0.536

High

229955

ATD3B
ATPase family AAA domain-containing protein 3B

1

4

High-throughput

0.536

High

229956

CYTSA
Cytospin-A

1

7

High-throughput

0.536

High

229960

ZCH18
Zinc finger CCCH domain-containing protein 18

1

3

High-throughput

0.536

High

229963

LS14A
Protein LSM14 homolog A

1

2

High-throughput

0.536

High

229965

DDX1
ATP-dependent RNA helicase DDX1

1

5

High-throughput

0.536

High

229966

ELMO1
Engulfment and cell motility protein 1

1

1

High-throughput

0.536

High

229968

LRC59
Leucine-rich repeat-containing protein 59

1

4

High-throughput

0.536

High

229971

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

1

1

High-throughput

0.536

High

229972

RAB3I
Rab-3A-interacting protein

1

1

High-throughput

0.536

High

229973

DDX23
Probable ATP-dependent RNA helicase DDX23

1

3

High-throughput

0.536

High

229978

WDR26
WD repeat-containing protein 26

1

5

High-throughput

0.536

High

229979

WDR6
tRNA

1

13

High-throughput

0.536

High

229983

AKA11
A-kinase anchor protein 11

1

1

High-throughput

0.536

High

229986

EIF3L
Eukaryotic translation initiation factor 3 subunit L

1

1

High-throughput

0.536

High

229914

S10A8
Protein S100-A8

1

3

High-throughput

0.515

High

229916

S10A9
Protein S100-A9

1

3

High-throughput

0.515

High

229950

KPRA
Phosphoribosyl pyrophosphate synthase-associated protein 1

1

5

High-throughput

0.515

High

229906

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

1

0

High-throughput

0.513

High

229935

EIF3E
Eukaryotic translation initiation factor 3 subunit E

1

0

High-throughput

0.513

High

229951

NDUA9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

1

0

High-throughput

0.513

High

229954

TM201
Transmembrane protein 201

1

0

High-throughput

0.513

High

229961

PAF1
RNA polymerase II-associated factor 1 homolog

1

0

High-throughput

0.513

High

229977

PININ
Pinin

1

0

High-throughput

0.513

High

229913

A4
Amyloid-beta precursor protein

1

4

High-throughput

0.501

High

124688

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

2

High-throughput

0.489

High

150139

AP3D1
AP-3 complex subunit delta-1

1

4

High-throughput

0.489

High

229921

SON
Protein SON

1

5

High-throughput

0.489

High

229953

PRC2B
Protein PRRC2B

1

4

High-throughput

0.489

High

229970

ELMO2
Engulfment and cell motility protein 2

1

1

High-throughput

0.489

High

229988

E41L3
Band 4.1-like protein 3

1

9

High-throughput

0.489

High

229930

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

12

Small-scale

0.481

High

229964

FBX25
F-box only protein 25

1

0

Small-scale

0.480

High

229918

BIP
Endoplasmic reticulum chaperone BiP

1

7

High-throughput

0.479

High

229919

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.479

High

229936

1433G
14-3-3 protein gamma

1

20

High-throughput

0.479

High

229938

1433E
14-3-3 protein epsilon

1

20

High-throughput

0.479

High

229939

SKP1
S-phase kinase-associated protein 1

1

2

Small-scale

0.479

High

229945

CUL1
Cullin-1

1

5

Small-scale

0.479

High

229910

IGHA2
Immunoglobulin heavy constant alpha 2

1

1

High-throughput

0.437

High

229959

K2C1B
Keratin, type II cytoskeletal 1b

1

2

High-throughput

0.437

High

229941

PRB3
Basic salivary proline-rich protein 3

1

2

High-throughput

0.407

High

64507

ZSWM8
Zinc finger SWIM domain-containing protein 8

1

0

High-throughput

0.279

Low

229957

RM14
Large ribosomal subunit protein uL14m

1

0

High-throughput

0.279

Low

229962

TM102
Transmembrane protein 102

1

0

High-throughput

0.279

Low

229969

RM38
Large ribosomal subunit protein mL38

1

0

High-throughput

0.279

Low

229981

NDUBB
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024