HitPredict

Interactor 1: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Interactor 2: RN128 (Q8TEB7)
E3 ubiquitin-protein ligase RNF128 (EC 2.3.2.27) (Gene related to anergy in lymphocytes protein) (GRAIL) (RING finger protein 128) (RING-type E3 ubiquitin transferase RNF128)
Gene: RNF128

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	19549727
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_2
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006511 - ubiquitin-dependent protein catabolic process GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 158 Hs			1 428
+	Hs
		849382 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		RN128_HUMAN (1-428): 2.78e-148: 429: 100.00
+	Hs
		1356934 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		RN150_HUMAN (10-428): 1e-96: 298: 37.19
+	Hs
		849485 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		RN150_HUMAN (10-428): 1e-96: 298: 37.19
+	Hs
		1204871 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		GOLI_HUMAN (24-386): 6.57e-81: 257: 37.06
+	Hs
		849359 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		GOLI_HUMAN (24-386): 6.57e-81: 257: 37.06
+	Hs
		207572 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		RNF13_HUMAN (59-408): 5.89e-66: 217: 20.68
+	Hs
		207545 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		RNF13_HUMAN (59-408): 5.89e-66: 217: 20.68
+	Hs
		1332598 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		RN167_HUMAN (39-371): 5.4e-65: 213: 20.17
+	Hs
		849446 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		RN167_HUMAN (39-371): 5.4e-65: 213: 20.17
+	Hs
		1148281 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		RNF43_HUMAN (53-406): 2.06e-51: 186: 17.69
+	Hs
		849341 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		RNF43_HUMAN (53-406): 2.06e-51: 186: 17.69
+	Hs
		1262545 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		ZNRF4_HUMAN (57-373): 5.95e-47: 168: 18.79
+	Hs
		849385 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		ZNRF4_HUMAN (57-373): 5.95e-47: 168: 18.79
+	Hs
		1356614 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		AMFR_HUMAN (158-410): 7.98e-31: 127: 14.51
+	Hs
		849484 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		AMFR_HUMAN (158-410): 7.98e-31: 127: 14.51
+	Hs
		1377467 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		RN115_HUMAN (252-355): 7.64e-27: 111: 37.50
+	Hs
		849497 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		RN115_HUMAN (252-355): 7.64e-27: 111: 37.50
+	Hs
		849449 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		RN122_HUMAN (195-321): 2.53e-26: 105: 25.98
+	Hs
		1170316 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		ARK2C_HUMAN (265-328): 6.45e-09: 59.3: 37.31
+	Hs
		849350 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		ARK2C_HUMAN (265-328): 6.45e-09: 59.3: 37.31