Protein: AAKG2
5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma2) (AMPK subunit gamma-2) (H91620p)

Gene: AAKG2, PRKAG2
Organism: Homo sapiens
Interactions: 72
UniProt ID: Q9UGJ0

Gene Ontology (top 5):
GO:0004679 - AMP-activated protein kinase activity
GO:0004862 - cAMP-dependent protein kinase inhibitor activity
GO:0005524 - ATP binding
GO:0005615 - extracellular space
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1095478

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

10

18

High-throughput

0.977

High

225717

AAKB2
5'-AMP-activated protein kinase subunit beta-2

8

18

Small-scale

0.969

High

1459552

AAKB1
5'-AMP-activated protein kinase subunit beta-1

7

17

Small-scale

0.966

High

930813

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

7

18

High-throughput

0.966

High

930379

AAKG1
5'-AMP-activated protein kinase subunit gamma-1

3

16

Small-scale

0.849

High

1402689

DCR1C
Protein artemis

3

1

High-throughput

0.656

High

1412043

WDR83
WD repeat domain-containing protein 83

3

1

High-throughput

0.609

High

1459547

AAKG2
5'-AMP-activated protein kinase subunit gamma-2

1

13

High-throughput

0.575

High

1454266

STIM2
Stromal interaction molecule 2

2

1

High-throughput

0.574

High

920522

DAPK1
Death-associated protein kinase 1

1

4

High-throughput

0.536

High

1459553

MFHA1
Malignant fibrous histiocytoma-amplified sequence 1

1

2

High-throughput

0.536

High

365488

PGK1
Phosphoglycerate kinase 1

1

1

High-throughput

0.536

High

447888

TPM3
Tropomyosin alpha-3 chain

1

3

High-throughput

0.536

High

464224

TPM2
Tropomyosin beta chain

1

3

High-throughput

0.536

High

482976

TPM1
Tropomyosin alpha-1 chain

1

3

High-throughput

0.536

High

535954

MYH3
Myosin-3

1

6

High-throughput

0.536

High

551637

NFH
Neurofilament heavy polypeptide

1

7

High-throughput

0.536

High

556883

MYH1
Myosin-1

1

9

High-throughput

0.536

High

556965

MYH7
Myosin-7

1

9

High-throughput

0.536

High

563037

MYH6
Myosin-6

1

9

High-throughput

0.536

High

563075

MYH8
Myosin-8

1

7

High-throughput

0.536

High

585827

PHKG2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform

1

10

High-throughput

0.536

High

670030

MCM3
DNA replication licensing factor MCM3

1

3

High-throughput

0.536

High

687738

SYTC
Threonine--tRNA ligase 1, cytoplasmic

1

2

High-throughput

0.536

High

861322

MAP1B
Microtubule-associated protein 1B

1

2

High-throughput

0.536

High

892519

GUAA
GMP synthase [glutamine-hydrolyzing]

1

1

High-throughput

0.536

High

995500

TPM4
Tropomyosin alpha-4 chain

1

3

High-throughput

0.536

High

1038720

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

2

High-throughput

0.536

High

1110313

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

3

High-throughput

0.536

High

1121908

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

9

High-throughput

0.536

High

1122372

SCRIB
Protein scribble homolog

1

2

High-throughput

0.536

High

1128561

DSC3
Desmocollin-3

1

1

High-throughput

0.536

High

1289001

NHRF4
Na(+)/H(+) exchange regulatory cofactor NHE-RF4

1

2

High-throughput

0.536

High

1433225

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

2

High-throughput

0.536

High

1459549

MYH2
Myosin-2

1

8

High-throughput

0.536

High

1459554

MYH4
Myosin-4

1

7

High-throughput

0.536

High

1142423

PDIA6
Protein disulfide-isomerase A6

1

1

High-throughput

0.515

High

116882

I6L9F6
NEFL protein

1

1

High-throughput

0.515

High

167133

GEMI2
Gem-associated protein 2

1

0

High-throughput

0.513

High

176723

PUR4
Phosphoribosylformylglycinamidine synthase

1

0

High-throughput

0.513

High

261305

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.513

High

1418704

LOXE3
Hydroperoxide isomerase ALOXE3

1

0

High-throughput

0.513

High

423393

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.493

High

1108255

SQSTM
Sequestosome-1

1

0

High-throughput

0.493

High

469345

ASNS
Asparagine synthetase [glutamine-hydrolyzing]

1

1

High-throughput

0.479

High

664523

ALAT1
Alanine aminotransferase 1

1

1

High-throughput

0.479

High

915491

HMGA2
High mobility group protein HMGI-C

1

1

High-throughput

0.479

High

1008652

MAP1A
Microtubule-associated protein 1A

1

1

High-throughput

0.479

High

1121359

TRI14
Tripartite motif-containing protein 14

1

1

High-throughput

0.479

High

1246170

TRAF7
E3 ubiquitin-protein ligase TRAF7

1

2

High-throughput

0.479

High

1459548

XPO7
Exportin-7

1

4

High-throughput

0.479

High

1459551

RT16
Small ribosomal subunit protein bS16m

1

1

High-throughput

0.479

High

634978

NTF3
Neurotrophin-3

1

0

High-throughput

0.458

High

767364

MERL
Merlin

1

0

High-throughput

0.458

High

1081275

PLCX2
PI-PLC X domain-containing protein 2

1

0

High-throughput

0.458

High

1164332

CDO1
Cysteine dioxygenase type 1

1

0

High-throughput

0.458

High

1273879

NLRP9
NACHT, LRR and PYD domains-containing protein 9

1

0

High-throughput

0.458

High

1411059

ZN559
Zinc finger protein 559

1

0

High-throughput

0.458

High

1433369

GOLP3
Golgi phosphoprotein 3

1

0

High-throughput

0.458

High

1315556

ULK2
Serine/threonine-protein kinase ULK2

1

13

High-throughput

0.445

High

1459550

RPC10
DNA-directed RNA polymerase III subunit RPC10

1

1

High-throughput

0.445

High

1459556

S4A4
Electrogenic sodium bicarbonate cotransporter 1

1

3

High-throughput

0.445

High

1385712

ENTR1
Endosome-associated-trafficking regulator 1

1

1

High-throughput

0.437

High

1133811

SL9A5
Sodium/hydrogen exchanger 5

1

2

High-throughput

0.407

High

1459555

S4A7
Sodium bicarbonate cotransporter 3

1

3

High-throughput

0.407

High

1131426

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.279

Low

1337093

Q8NE08
COL25A1 protein

1

0

High-throughput

0.268

Low

190512

COPT1
High affinity copper uptake protein 1

1

0

Small-scale

0.261

Low

902359

SCNND
Epithelial sodium channel subunit delta

1

0

High-throughput

0.249

Low

1248259

KCNT2
Potassium channel subfamily T member 2

1

0

High-throughput

0.249

Low

1447065

TSSP
Thymus-specific serine protease

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025