HitPredict

Interactor 1: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Interactor 2: TRI55 (Q9BYV6)
Tripartite motif-containing protein 55 (EC 2.3.2.27) (Muscle-specific RING finger protein 2) (MuRF-2) (MuRF2) (RING finger protein 29)
Gene: TRIM55

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	1.00	0.757

Property	Details
Experiments	11927605, 15802564
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 158 Hs			1 548
+	Hs
		262201 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		TRIM3_HUMAN (7-525): 5.4e-80: 267: 16.64
+	Hs
		262161 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		TRIM3_HUMAN (7-525): 5.4e-80: 267: 16.64
+	Hs
		1336390 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		TRI39_HUMAN (17-414): 4.23e-77: 254: 15.74
+	Hs
		1317493 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		TRI54_HUMAN (1-353): 3.29e-78: 252: 62.54
+	Hs
		1318738 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		TRIM2_HUMAN (6-525): 1.61e-74: 252: 16.48
+	Hs
		584907 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		RO52_HUMAN (12-405): 3.8e-74: 245: 15.87
+	Hs
		1285831 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		TRI43_HUMAN (13-395): 3.07e-73: 242: 13.06
+	Hs
		849320 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		TIF1B_HUMAN (18-534): 7.29e-67: 233: 15.37
+	Hs
		1318719 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		TRIM5_HUMAN (13-396): 3.08e-68: 230: 14.32
+	Hs
		1151762 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		Q6GX22_HUMAN (17-367): 1.43e-63: 222: 21.28
+	Hs
		1318358 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		TRIM8_HUMAN (18-465): 8.09e-65: 222: 18.25
+	Hs
		1356055 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		TRIM1_HUMAN (17-367): 3.2e-63: 222: 21.28
+	Hs
		537142 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		TRI27_HUMAN (12-434): 9.25e-65: 221: 14.51
+	Hs
		849314 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		TRI26_HUMAN (12-339): 5.62e-65: 222: 16.23
+	Hs
		536760 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		TRI27_HUMAN (12-434): 9.25e-65: 221: 14.51
+	Hs
		1313765 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		TRI62_HUMAN (19-289): 8.04e-64: 217: 20.80
+	Hs
		1318532 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		TRI31_HUMAN (12-426): 1.42e-62: 213: 17.35
+	Hs
		1377469 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		TRI17_HUMAN (18-368): 7.08e-62: 212: 16.71
+	Hs
		175730 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		TRI18_HUMAN (46-330): 5.85e-60: 211: 23.43
+	Hs
		175653 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		TRI18_HUMAN (46-330): 5.85e-60: 211: 23.43