HitPredict

Interactor 1: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Interactor 2: RN115 (Q9Y4L5)
E3 ubiquitin-protein ligase RNF115 (EC 2.3.2.27) (RING finger protein 115) (RING-type E3 ubiquitin transferase RNF115) (Rab7-interacting RING finger protein) (Rabring 7) (Zinc finger protein 364)
Gene: RNF115

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.767

Property	Details
Experiments	28122985, 18819927
Identification Methods	pull down, two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_2
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 158 Hs			1 304
+	Hs
		1377467 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		RN115_HUMAN (1-304): 2.11e-80: 247: 100.00
+	Hs
		849497 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		RN115_HUMAN (1-304): 2.11e-80: 247: 100.00
+	Hs
		1313520 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		RN126_HUMAN (17-282): 5.46e-59: 192: 44.37
+	Hs
		849428 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		RN126_HUMAN (17-282): 5.46e-59: 192: 44.37
+	Dm
		639401 UBCD1_DROME (4-157): 4.5e-74: 220: 35.71		IRU_DROME (12-301): 5.25e-50: 171: 26.25
+	Zm
		74334 B4FC97_MAIZE (4-157): 8.79e-75: 221: 35.71		B6U926_MAIZE (11-292): 2.99e-48: 167: 26.82
+	Hs
		196372 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		PJA2_HUMAN (5-296): 1.59e-40: 151: 18.45
+	Hs
		196282 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		PJA2_HUMAN (5-296): 1.59e-40: 151: 18.45
+	Hs
		196294 UB2D2_HUMAN (4-157): 2.44e-74: 220: 35.07		PJA2_HUMAN (5-296): 1.59e-40: 151: 18.45
+	Hs
		849382 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		RN128_HUMAN (49-301): 6.53e-39: 143: 21.53
+	Hs
		1356934 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		RN150_HUMAN (87-297): 5.62e-33: 127: 15.95
+	Hs
		849485 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		RN150_HUMAN (87-297): 5.62e-33: 127: 15.95
+	Hs
		849491 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		RNF6_HUMAN (55-276): 3.65e-31: 124: 20.89
+	Hs
		1204871 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		GOLI_HUMAN (58-298): 4.27e-29: 116: 15.95
+	Hs
		1327690 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		RNF38_HUMAN (85-271): 1.54e-28: 116: 23.40
+	Hs
		1349753 UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42		RN181_HUMAN (192-294): 1.74e-31: 116: 34.58
+	Hs
		849359 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		GOLI_HUMAN (58-298): 4.27e-29: 116: 15.95
+	Hs
		849443 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		RNF38_HUMAN (85-271): 1.54e-28: 116: 23.40
+	Hs
		849467 UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12		RN181_HUMAN (192-294): 1.74e-31: 116: 34.58
+	Hs
		919772 UB2D2_HUMAN (4-157): 2.44e-74: 220: 35.07		GOLI_HUMAN (58-298): 4.27e-29: 116: 15.95