HitPredict

Interactor 1: UBC9 (P63280)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (mUBC9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I)
Gene: Ube2i

Interactor 2: SUMO3 (Q9Z172)
Small ubiquitin-related modifier 3 (SUMO-3) (SMT3 homolog 1) (Ubiquitin-like protein SMT3A) (Smt3A)
Gene: SUMO3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	20077568
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Rad60-SLD~UQ_con
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016604 - nuclear body GO:0016925 - protein sumoylation and 1 others more... GO:0019789 - SUMO transferase activity
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 158 Mm			1 110
+	Rn
		930510 UBC9_RAT (1-158): 1.43e-70: 211: 100.00		SUMO3_RAT (1-110): 9.16e-56: 170: 94.55
+	At
		1114967 SCE1_ARATH (2-155): 5.4e-72: 215: 66.23		SUMO2_ARATH (1-97): 2.31e-42: 136: 49.49
+	Hs
		879101 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		SUMO3_HUMAN (1-92): 2.66e-43: 138: 100.00
+	Hs
		902509 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		SUMO2_HUMAN (1-92): 9.19e-42: 134: 96.77
+	Hs
		928121 Q7KZS0_HUMAN (1-137): 2.27e-71: 214: 100.00		SUMO1_HUMAN (1-95): 5.43e-39: 127: 47.00
+	At
		1114966 SCE1_ARATH (2-155): 5.4e-72: 215: 66.23		SUMO3_ARATH (1-96): 9.49e-38: 124: 40.21
+	Hs
		102167 Q7KZS0_HUMAN (1-137): 2.27e-71: 214: 100.00		SUMO5_HUMAN (1-95): 9.68e-38: 124: 45.00
+	At
		878960 SCE1_ARATH (2-155): 5.4e-72: 215: 66.23		SUMO1_ARATH (2-90): 2.66e-37: 123: 47.19
+	Hs
		928056 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		SUMO1_HUMAN (1-95): 5.43e-39: 127: 47.00
+	Mm
		928242 UBC9_MOUSE (1-158): 1.43e-70: 211: 100.00		SUMO1_MOUSE (1-95): 5.43e-39: 127: 47.00
+	Hs
		102156 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		SUMO5_HUMAN (1-95): 9.68e-38: 124: 45.00
+	Sp
		140897 UBC9_SCHPO (1-157): 1.37e-66: 201: 66.24		PMT3_SCHPO (2-94): 8.33e-40: 130: 49.46
+	Dm
		332535 Q7KNM2_DROME (1-158): 1.41e-66: 201: 85.44		O97102_DROME (6-93): 5.69e-39: 127: 69.32
+	Ce
		879079 UBC9_CAEEL (1-157): 3.2e-68: 205: 76.43		SUMO_CAEEL (1-92): 2.37e-36: 120: 43.48
+	Zm
		74333 B4FC97_MAIZE (4-157): 8.79e-75: 221: 35.71		B6TQW3_MAIZE (3-90): 2.3e-26: 99.3: 30.68
+	At
		1114930 SCE1_ARATH (2-155): 5.4e-72: 215: 66.23		Q8LCF9_ARATH (2-90): 2.35e-26: 98.9: 26.67
+	Mm
		140343 UBC9_MOUSE (1-158): 1.43e-70: 211: 100.00		NF2IP_MOUSE (5-85): 8.28e-23: 92.7: 28.05
+	Sc
		841454 UBC9_YEAST (1-156): 3.53e-61: 187: 56.41		SMT3_YEAST (2-94): 4.19e-33: 112: 44.09