Interactor 1: PP2AA (P63330)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PP2A-alpha) (EC 3.1.3.16)
Gene: Ppp2ca

Interactor 2: 2AAA (Q76MZ3)
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2A subunit A isoform PR65-alpha) (PP2A subunit A isoform R1-alpha)
Gene: Ppp2r1a

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.757

The method score is based on:

Property Details
Experiments 9920888, 19818709
Identification Methods two hybrid, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HEAT~Metallophos, HEAT_2~Metallophos
Common GO terms GO:0000159 - protein phosphatase type 2A complex
GO:0000775 - chromosome, centromeric region
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 6 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 309
Mm

1 589
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Mm
+ Sp
+ Hs
+ Hs
+ Sc
+ Hs
+ Sc
+ Hs
+ Bt
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024