HitPredict

Interactor 1: HSP72 (P54652)
Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2) (Heat shock protein family A member 2)
Gene: HSPA2

Interactor 2: ILK (Q13418)
Scaffold protein ILK (ILK-1) (ILK-2) (Inactive integrin-linked kinase) (p59ILK)
Gene: ILK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane and 1 others more... GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 639 Hs			1 452
+	Hs
		761384 HS71L_HUMAN (2-639): 0: 952: 81.90		ILK_HUMAN (1-452): 5.36e-147: 428: 100.00
+	Hs
		537103 HSP7C_HUMAN (3-616): 0: 946: 87.95		ILK_HUMAN (1-452): 5.36e-147: 428: 100.00
+	Hs
		600805 HSP76_HUMAN (2-639): 0: 945: 77.45		ILK_HUMAN (1-452): 5.36e-147: 428: 100.00
+	Mm
		237358 HSP7C_MOUSE (3-616): 0: 945: 87.79		ILK_MOUSE (1-452): 2.33e-146: 426: 99.56
+	Hs
		439923 HSP7C_HUMAN (3-616): 0: 946: 87.95		LCK_HUMAN (167-449): 1.45e-109: 334: 21.99
+	Hs
		439939 HSP76_HUMAN (2-639): 0: 945: 77.45		LCK_HUMAN (167-449): 1.45e-109: 334: 21.99
+	Hs
		536396 HSP7C_HUMAN (3-616): 0: 946: 87.95		SRC_HUMAN (173-448): 1.45e-98: 307: 24.56
+	Hs
		462958 HSP7C_HUMAN (3-616): 0: 946: 87.95		YES_HUMAN (176-448): 5.04e-98: 305: 26.60